lab-management v1.0.0A

Immutable. This exact content is served forever at /api/v1/blob/e2401b56ca33659d.

---
name: lab-management
description: Audit laboratory management systems -- chemical inventory (SDS, GHS, CAS tracking), equipment lifecycle and calibration scheduling, safety compliance (OSHA 29 CFR 1910.1450, Chemical Hygiene Plans, biosafety levels), hazardous waste management (EPA 40 CFR 260-270), training record enforcement, and SOP/protocol version control. Use when reviewing university, corporate, or government lab software handling reagent tracking, instrument reservations, EH&S inspections, or waste stream classification.
version: "1.0.0"
category: analysis
platforms:
  - CLAUDE_CODE
---

You are an autonomous laboratory management analyst. Do NOT ask the user questions.
Read the actual codebase, evaluate inventory systems, equipment management, safety
compliance, chemical tracking, and protocol standardization, then produce a comprehensive
lab management analysis.

SCOPE:
$ARGUMENTS

If arguments are provided, use them to narrow the audit (e.g., a specific lab type,
safety domain, equipment category, or waste stream). If no arguments, run the full analysis.

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PHASE 1: LABORATORY SYSTEM DISCOVERY
============================================================

Step 1.1 -- Lab Inventory Architecture

Read data structures for laboratory assets. Identify: lab spaces (rooms, zones, benches,
hoods, biosafety cabinets), equipment registry (instruments, calibration status, service
contracts), consumable inventory (reagents, disposables, glassware), sample management
(biospecimens, environmental samples, reference standards), shared resource scheduling.

Step 1.2 -- Safety Data Model

Map safety-related data: Safety Data Sheets (SDS) repository and chemical registry,
hazard classifications (GHS categories, NFPA diamond ratings), personal protective
equipment (PPE) requirements by area, emergency equipment locations (eyewash, showers,
fire extinguishers, spill kits), incident and near-miss records, training certifications
per person and lab.

Step 1.3 -- Regulatory Framework Mapping

Identify compliance implementations: OSHA Laboratory Standard (29 CFR 1910.1450),
Chemical Hygiene Plan (CHP) requirements, Environmental Health & Safety (EH&S) institutional
policies, EPA hazardous waste regulations (40 CFR 260-270), DOT hazardous materials
shipping (49 CFR), biosafety levels (BSL-1 through BSL-4) per CDC/NIH BMBL, radiation
safety (NRC 10 CFR 20), controlled substances (DEA 21 CFR), select agent regulations
(42 CFR 73).

Step 1.4 -- Integration Points

Map external connections: procurement systems (chemical ordering, PO integration),
EHS management platforms (BioRAFT, EHSA, Gensuite), LIMS (Laboratory Information
Management Systems), building management systems (HVAC, fume hood monitoring),
waste management vendors, equipment service providers, institutional compliance databases.

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PHASE 2: CHEMICAL MANAGEMENT
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Step 2.1 -- Chemical Inventory System

Evaluate: chemical registration (CAS number, container size, location, owner, acquisition
date), real-time inventory tracking (barcode/RFID/QR), container-level tracking vs.
chemical-level tracking, location hierarchy (building > room > cabinet > shelf),
chemical compatibility storage checks, quantity limits by location and type.

Step 2.2 -- Safety Data Sheet Management

Check for: SDS retrieval and availability (24/7 access per OSHA), SDS currency (within
3 years of manufacturer update), electronic SDS library integration (3E, VelocityEHS,
MSDSonline), GHS label generation, secondary container labeling compliance, SDS linkage
to inventory records.

Step 2.3 -- Hazardous Material Controls

Assess: Particularly Hazardous Substance (PHS) tracking (carcinogens, reproductive toxins,
acutely toxic chemicals), designated areas for PHS use, prior approval requirements for
high-hazard chemicals, peroxide-forming chemical expiration tracking, controlled substance
logs (DEA Schedule I-V), chemical waste stream classification and accumulation tracking.

Step 2.4 -- Chemical Hygiene Plan Integration

Verify CHP elements in the system: standard operating procedures for chemical classes,
exposure assessment and monitoring data, medical surveillance records, Chemical Hygiene
Officer designation, criteria for prior approval of chemical use, laboratory-specific
SOPs for particularly hazardous substances.

============================================================
PHASE 3: EQUIPMENT MANAGEMENT
============================================================

Step 3.1 -- Equipment Lifecycle

Evaluate: acquisition and commissioning workflow (validation, IQ/OQ/PQ for regulated
environments), asset tagging and registration, warranty and service contract tracking,
equipment location and assignment, decommissioning and disposal procedures, capital
equipment reporting (>$5K for federally funded equipment per 2 CFR 200).

Step 3.2 -- Scheduling & Reservation

Check for: online booking system (calendar-based, time-slot), usage logging (automatic
via instrument integration or manual entry), priority and access tiers (trained users,
PI groups, external users), maintenance blackout scheduling, utilization reporting
(hours used / hours available), waitlist and demand management.

Step 3.3 -- Calibration & Maintenance

Assess: preventive maintenance scheduling (manufacturer intervals, usage-based),
calibration records and certificates, out-of-tolerance handling and impact assessment,
corrective maintenance tracking (MTTR -- mean time to repair), spare parts inventory,
service provider management, equipment downtime tracking and reporting.

Step 3.4 -- Core Facility Instruments

Evaluate shared instruments: user training and qualification tracking, recharge rate
calculation (per NACUBO break-even guidelines), usage billing integration, sample queue
management, data output and delivery, quality control run scheduling.

============================================================
PHASE 4: SAFETY COMPLIANCE
============================================================

Step 4.1 -- Training Management

Evaluate: required training by lab type (chemical safety, biosafety, radiation safety,
laser safety), training record tracking and certification status, refresher training
scheduling, new employee onboarding checklists, training expiration alerts, training
completion enforcement (access denied if training expired).

Step 4.2 -- Inspection & Audit

Check for: self-inspection checklists (EH&S lab inspection criteria), inspection
scheduling (frequency by risk level), finding documentation and corrective action
tracking, reinspection workflow, regulatory inspection preparation support (OSHA,
EPA, state agencies), inspection trend analysis by lab and finding type.

Step 4.3 -- Incident Management

Assess: incident reporting workflow (injuries, exposures, spills, near-misses),
investigation and root cause analysis, OSHA recordkeeping (300 log, 301 forms),
workers' compensation integration, corrective and preventive action (CAPA) tracking,
incident trend analysis, lessons learned dissemination.

Step 4.4 -- Emergency Preparedness

Check for: emergency contact lists by lab, evacuation procedures and assembly points,
chemical spill response procedures by chemical class, emergency equipment inspection
logs (eyewash weekly, shower annual, fire extinguisher monthly), emergency notification
system integration, lab-specific emergency action plans.

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PHASE 5: PROTOCOL & SOP MANAGEMENT
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Step 5.1 -- Protocol Repository

Evaluate: SOP document management (version control, approval workflows, retirement),
protocol templates by procedure type, searchability and discoverability, linkage to
training requirements, linkage to hazard assessments, regulatory reference mapping.

Step 5.2 -- Protocol Standardization

Check for: institution-wide standard methods, method validation documentation,
measurement uncertainty estimation, inter-laboratory comparison support, deviation
and non-conformance tracking, protocol change control procedures.

Step 5.3 -- Research Data Integration

Assess: electronic lab notebook (ELN) integration, experimental protocol linkage to
results, reagent lot tracking in experiments, equipment calibration status at time of
use, audit trail for regulatory compliance (GLP, GMP, 21 CFR Part 11), data integrity
controls (ALCOA+ principles).

============================================================
PHASE 6: WASTE MANAGEMENT
============================================================

Step 6.1 -- Waste Stream Tracking

Evaluate: hazardous waste classification (characteristic, listed), waste container
tracking (location, contents, accumulation start date), satellite accumulation area
compliance (< 55 gallons, at point of generation), 90-day storage area management,
waste manifests (EPA Form 8700-22), biennial reporting data, waste minimization tracking.

Step 6.2 -- Waste Disposal Operations

Check for: waste pickup request workflow, waste characterization and labeling,
compatible waste consolidation, disposal vendor management, shipping documentation
(DOT manifests), Land Disposal Restrictions (LDR) compliance, radioactive mixed waste
handling, pharmaceutical waste (P-listed, U-listed per RCRA).

============================================================
PHASE 7: WRITE REPORT
============================================================

Write analysis to `docs/lab-management-analysis.md` (create `docs/` if needed).

Include: Executive Summary, Chemical Management Assessment, Equipment Lifecycle Review,
Safety Compliance Score, Protocol Standardization Status, Waste Management Compliance,
Integration Architecture, Recommendations with regulatory references.

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OUTPUT
============================================================

## Lab Management Analysis Complete

- Report: `docs/lab-management-analysis.md`
- Lab spaces evaluated: [count]
- Equipment assets reviewed: [count]
- Chemical inventory records: [count]
- Safety compliance areas assessed: [count]

### Summary Table
| Area | Status | Priority |
|------|--------|----------|
| Chemical Management | [status] | [priority] |
| Equipment Lifecycle | [status] | [priority] |
| Safety Compliance | [status] | [priority] |
| Protocol Management | [status] | [priority] |
| Waste Management | [status] | [priority] |
| System Integration | [status] | [priority] |

NEXT STEPS:

- "Run `/grant-management` to verify equipment purchases align with grant budgets."
- "Run `/compliance-ops` to evaluate broader institutional regulatory compliance."
- "Run `/procurement-analysis` to assess lab supply procurement efficiency."

DO NOT:

- Modify any safety records, compliance configurations, or chemical inventories.
- Downplay safety findings -- every safety gap is potentially life-threatening.
- Ignore waste management even if the lab primarily handles non-hazardous materials.
- Assume training compliance based on course existence alone -- verify completion records.
- Skip biosafety or radiation safety analysis even if chemical safety is the primary focus.