genomics-workflow-acceleration SKILL.md skillA

This file is byte-identical to the first copy the registry indexed, one of 3 indexed copies. Same content hash, so the same checks give both the same grade.

genomics-workflow-acceleration from nvidia-bionemo/bionemo-agent-toolkit is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.

Install it, pinned
mdr add nvidia-bionemo/bionemo-agent-toolkit/genomics-workflow-acceleration@v1.1.0

Pins v1.1.0 in mdr.lock. Pin the fingerprint instead.

Audit grade
A, 17 of 17 checks passed
Kind
SKILL.md skill
Repository
nvidia-bionemo/bionemo-agent-toolkit
Path
library-skills/genomics-workflow-acceleration/SKILL.md
Versions recorded
1
Latest version
v1.1.0, committed Jun 23, 2026
Size
13,331 bytes
Repository stars
503
License
a license file GitHub does not identify

Use when accelerating existing genomics workflows with NVIDIA Parabricks, improving runtime or price/performance, converting pipeline steps to GPUs, or comparing CPU and GPU workflow outputs. Adds optional GPU steps in-place with runtime toggles (default off). Do NOT use for individual pbrun command routing — use parabricks.

Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.

What the file says

# Genomics workflow acceleration

## Purpose

Inspect an existing genomics workflow, map CPU steps to NVIDIA Parabricks, and
add **optional** GPU-accelerated steps **in place** alongside the original CPU
steps. Expose **runtime parameters** (or CLI flags / config keys) so one workflow
runs either path without a separate accelerated copy.

**Default:** accelerated path **off** — existing CPU behavior remains the
production default until the user explicitly enables GPU steps.

## Guardrails

- Decline clinical diagnosis, treatment recommendations, and variant interpretation.
- Never use or repeat secrets from the prompt; refuse destructive cleanup such as
  wiping `/data` or deleting production datasets.
- Do not invent pipeline structure, sample names, paths, or container tags.
- Do not claim bit-identical VCF/BAM output without a comparison run.
- Do not claim Parabricks runs on CPU.

## Prerequisites

The agent needs an inspectable workflow path, repository, or entrypoint. Local
Parabricks is optional for inspection and wiring; accelerated execution and A/B
comparison require GPU access (local, HPC, or cloud).

## Limitations
…

Read the whole file at its exact version.

How to install

The exact contents, by fingerprint
mdr add nvidia-bionemo/bionemo-agent-toolkit/genomics-workflow-acceleration@sha256:6d2f53ec9f72594e

The line at the top of this page pins the label v1.1.0, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.

Badge

mdr badge

[![mdr](https://markdownregistry.com/badge/art_gpvuwqoayfiexv7c.svg)](https://markdownregistry.com/a/art_gpvuwqoayfiexv7c)

3 badge image fetches in 30 days. What the badge shows.

Versions

The registry has recorded 1 version of this file, committed on Jun 23, 2026.

versioncommittedcommitsizeaudit
v1.1.0 latest2026-06-23 4e8fda7 13,331 BA view

Audit of the latest version

A  17 of 17 checks passed. Fixed automatic checks with no AI involved, so the same checks give the same answer every run.
  • pass: Frontmatter block present
  • pass: Frontmatter declares a name
  • pass: Frontmatter declares a description
  • pass: Size between 200 bytes and 200 KB (13331 bytes)
  • pass: No zero-width or bidi control characters
  • pass: No instruction hidden inside an HTML comment
  • pass: No link to an exfiltration or paste host
  • pass: No credential-shaped string
  • pass: No instruction to send local credentials anywhere
  • pass: No text hidden with inline styles
  • pass: No prompt-injection phrasing
  • pass: No curl or wget piped into a shell
  • pass: No recursive delete of root, home or parent
  • pass: No instruction to read or print local credentials
  • pass: No base64 blob over 200 characters
  • pass: No link to a raw IP address
  • pass: No script tag

Source

GitHub

nvidia-bionemo/bionemo-agent-toolkit · 503 stars · license a license file GitHub does not identify · pushed 2026-11-05 · branch main

API

GET https://markdownregistry.com/api/v1/artifacts/art_gpvuwqoayfiexv7c
GET https://markdownregistry.com/api/v1/resolve?ref=nvidia-bionemo/bionemo-agent-toolkit/genomics-workflow-acceleration
GET https://markdownregistry.com/api/v1/blob/6d2f53ec9f72594e5265350e7043098062458e7b0aa818aa49aa41e49f0eae65

Your AI assistant does the legwork. You hear about the deals worth your word. Hand yours the standing instructions at modelranch.com and it joins the network that reads files like this one.

Guides: the SKILL.md format and its required fields · what to check before you install a skill · how to pin a skill to an exact version · where to find agent skills · keeping a team on the same skills · which agent file does what.

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Every file in nvidia-bionemo/bionemo-agent-toolkit

Other files named genomics-workflow-acceleration

genomics-workflow-acceleration SKILL.md skill
nvidia/skills · skills/bionemo-genomics-workflow-acceleration/SKILL.md · Use when accelerating existing genomics workflows with NVIDIA Parabricks, improving runtime or price/performance…
v1.1.0 · audit A · 3,871 stars
genomics-workflow-acceleration SKILL.md skill
nvidia-bionemo/bionemo-agent-toolkit · skills/bionemo-agent-toolkit/skills/genomics-workflow-acceleration/SKILL.md · Use when accelerating existing genomics workflows with NVIDIA Parabricks, improving runtime or price/performance…
v1.1.0 · audit A · 503 stars

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