ligandmpnn SKILL.md skillA
This file is byte-identical to the first copy the registry indexed. Same content hash, so the same checks give both the same grade.
ligandmpnn from yichen-zju/claude-for-research is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.
mdr add yichen-zju/claude-for-research/ligandmpnn@git:20261014.9f2a5e0Pins git:20261014.9f2a5e0 in mdr.lock. Pin the fingerprint instead.
- Audit grade
- A, 17 of 17 checks passed
- Kind
- SKILL.md skill
- Repository
- yichen-zju/claude-for-research
- Path
claude/skills/ligandmpnn/SKILL.md- Versions recorded
- 1
- Latest version
- git:20261014.9f2a5e0, committed Oct 14, 2026
- Size
- 989 bytes
- Repository stars
- 10
- License
- none declared
Design protein sequences around ligand or small-molecule contexts with LigandMPNN-style workflows. Use when a task asks for ligand-aware protein design, residue redesign, constraints, or design ranking.
Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.
What the file says
# LigandMPNN Use this skill for ligand-aware protein sequence design. Workflow: 1. Record the input structure, ligand identity, chain/residue design mask, fixed residues, symmetry, and design objective. 2. Verify the execution route and model availability before running. 3. Save input structure, ligand file, residue masks, command, seeds, model version, generated FASTA, and score tables. 4. Filter outputs by constraint satisfaction, sequence diversity, known motifs, predicted structure confidence, and ligand-contact plausibility. 5. Send shortlisted designs through an independent structural or literature/database check before presenting them as candidates. Generated designs must remain tied to exact input structures and constraints.
Read the whole file at its exact version.
How to install
mdr add yichen-zju/claude-for-research/ligandmpnn@sha256:cd6a3be463341cbaThe line at the top of this page pins the label git:20261014.9f2a5e0, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.
[](https://markdownregistry.com/a/art_jzovaklzbpjxabk6)
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Versions
The registry has recorded 1 version of this file, committed on Oct 14, 2026.
Audit of the latest version
- pass: Frontmatter block present
- pass: Frontmatter declares a name
- pass: Frontmatter declares a description
- pass: Size between 200 bytes and 200 KB (989 bytes)
- pass: No zero-width or bidi control characters
- pass: No instruction hidden inside an HTML comment
- pass: No link to an exfiltration or paste host
- pass: No credential-shaped string
- pass: No instruction to send local credentials anywhere
- pass: No text hidden with inline styles
- pass: No prompt-injection phrasing
- pass: No curl or wget piped into a shell
- pass: No recursive delete of root, home or parent
- pass: No instruction to read or print local credentials
- pass: No base64 blob over 200 characters
- pass: No link to a raw IP address
- pass: No script tag
Source
yichen-zju/claude-for-research · 10 stars · license none declared · pushed 2026-10-21 · branch main
API
GET https://markdownregistry.com/api/v1/artifacts/art_jzovaklzbpjxabk6 GET https://markdownregistry.com/api/v1/resolve?ref=yichen-zju/claude-for-research/ligandmpnn GET https://markdownregistry.com/api/v1/blob/cd6a3be463341cba7795ee36c4158fafde5f8e15107818dd5b99451d13fc9c65
Your AI assistant does the legwork. You hear about the deals worth your word. Hand yours the standing instructions at modelranch.com and it joins the network that reads files like this one.
Guides: the SKILL.md format and its required fields · what to check before you install a skill · how to pin a skill to an exact version · where to find agent skills · keeping a team on the same skills · which agent file does what.
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