cosmic-database SKILL.md skillA

cosmic-database from marielynneblock/arcanum-artifex is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.

Install it, pinned
mdr add marielynneblock/arcanum-artifex/cosmic-database@git:20260710.0115f49

Pins git:20260710.0115f49 in mdr.lock. Pin the fingerprint instead.

Audit grade
A, 17 of 17 checks passed
Kind
SKILL.md skill
Repository
marielynneblock/arcanum-artifex
Path
skills/scientific/cosmic-database/SKILL.md
Versions recorded
5
Latest version
git:20260710.0115f49, committed Jul 10, 2026
First version recorded
Apr 6, 2026
Size
10,031 bytes
Repository stars
4
License
none declared

Access COSMIC cancer mutation database. Query somatic mutations, Cancer Gene Census, mutational signatures, gene fusions, for cancer research and precision oncology. Requires authentication.

Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.

What the file says

# COSMIC Database

## Overview

COSMIC (Catalogue of Somatic Mutations in Cancer) is the world's largest and most comprehensive database for exploring somatic mutations in human cancer. Access COSMIC's extensive collection of cancer genomics data, including millions of mutations across thousands of cancer types, curated gene lists, mutational signatures, and clinical annotations programmatically.

## When to Use This Skill

This skill should be used when:
- Downloading cancer mutation data from COSMIC
- Accessing the Cancer Gene Census for curated cancer gene lists
- Retrieving mutational signature profiles
- Querying structural variants, copy number alterations, or gene fusions
- Analysing drug resistance mutations
- Working with cancer cell line genomics data
- Integrating cancer mutation data into bioinformatics pipelines
- Researching specific genes or mutations in cancer contexts

## Prerequisites

### Account Registration
COSMIC requires authentication for data downloads:
- **Academic users**: Free access with registration at https://cancer.sanger.ac.uk/cosmic/register
- **Commercial users**: License required (contact QIAGEN)

### Python Requirements
```bash
…

Read the whole file at its exact version.

How to install

The exact contents, by fingerprint
mdr add marielynneblock/arcanum-artifex/cosmic-database@sha256:998186bbd480e6e9

The line at the top of this page pins the label git:20260710.0115f49, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.

Badge

mdr badge

[![mdr](https://markdownregistry.com/badge/art_m4dh4i2pplqnuzrn.svg)](https://markdownregistry.com/a/art_m4dh4i2pplqnuzrn)

5 badge image fetches in 30 days. What the badge shows.

Versions

The registry has recorded 5 versions of this file, between Apr 6, 2026 and Jul 10, 2026, about one every 24 days.

versioncommittedcommitsizeaudit
git:20260710.0115f49 latest2026-07-10 0115f49 10,031 BA view · diff
git:20260710.d1b3aa82026-07-10 d1b3aa8 10,031 BA view · diff
git:20260710.ffb34002026-07-10 ffb3400 10,031 BA view · diff
git:20260515.b861afb2026-05-15 b861afb 10,031 BA view · diff
git:20260406.05dff342026-04-06 05dff34 10,032 BA view

Audit of the latest version

A  17 of 17 checks passed. Fixed automatic checks with no AI involved, so the same checks give the same answer every run.
  • pass: Frontmatter block present
  • pass: Frontmatter declares a name
  • pass: Frontmatter declares a description
  • pass: Size between 200 bytes and 200 KB (10031 bytes)
  • pass: No zero-width or bidi control characters
  • pass: No instruction hidden inside an HTML comment
  • pass: No link to an exfiltration or paste host
  • pass: No credential-shaped string
  • pass: No instruction to send local credentials anywhere
  • pass: No text hidden with inline styles
  • pass: No prompt-injection phrasing
  • pass: No curl or wget piped into a shell
  • pass: No recursive delete of root, home or parent
  • pass: No instruction to read or print local credentials
  • pass: No base64 blob over 200 characters
  • pass: No link to a raw IP address
  • pass: No script tag

Source

GitHub

marielynneblock/arcanum-artifex · 4 stars · license none declared · pushed 2026-09-19 · branch main

API

GET https://markdownregistry.com/api/v1/artifacts/art_m4dh4i2pplqnuzrn
GET https://markdownregistry.com/api/v1/resolve?ref=marielynneblock/arcanum-artifex/cosmic-database
GET https://markdownregistry.com/api/v1/blob/998186bbd480e6e9c69bb9c742ff6cd7e0f4da5451d398a8058533a91ed6fb3c

Your AI assistant does the legwork. You hear about the deals worth your word. Hand yours the standing instructions at modelranch.com and it joins the network that reads files like this one.

Guides: the SKILL.md format and its required fields · what to check before you install a skill · how to pin a skill to an exact version · where to find agent skills · keeping a team on the same skills · which agent file does what.

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Every file in marielynneblock/arcanum-artifex

Other files named cosmic-database

cosmic-database SKILL.md skill
jaechang-hits/sciagent-skills · skills/genomics-bioinformatics/databases/cosmic-database/SKILL.md · Query COSMIC for cancer somatic mutations, gene census, mutational signatures, drug resistance variants. REST API v3.1…
git:20260528.3e3f998 · audit A · 386 stars

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