rfdiffusion-nim SKILL.md skillA
rfdiffusion-nim from nvidia/skills is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.
mdr add nvidia/skills/rfdiffusion-nim@git:20261001.3ec135cPins git:20261001.3ec135c in mdr.lock. Pin the fingerprint instead.
- Audit grade
- A, 17 of 17 checks passed
- Kind
- SKILL.md skill
- Repository
- nvidia/skills
- Path
skills/bionemo-rfdiffusion-nim/SKILL.md- Versions recorded
- 1
- Latest version
- git:20261001.3ec135c, committed Oct 1, 2026
- Size
- 5,374 bytes
- Repository stars
- 3,871
- License
- Apache-2.0
Run RFDiffusion protein backbone design via NVIDIA NIM. Use for de novo protein backbones, motif scaffolding, binder design, hotspot residues, contigs syntax, diffusion steps, hosted NVIDIA API calls, local Docker deployment, and PDB backbone outputs for ProteinMPNN sequence design.
Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.
What the file says
# RFDiffusion NIM Design protein backbone PDBs for de novo proteins, motif scaffolds, and binders. Use this guide for first-pass hosted/local usage; load supplemental files only when needed: - `references/api.md`: exact endpoints, schemas, Docker flags, response fields. - `references/science.md`: design modes, strengths, limits, and handoffs. - `references/parameters.md`: contigs, hotspots, steps, and seeds. - `references/validation.md`: PDB, contig, and artifact sanity checks. - `references/examples.md`: compact hosted/local request patterns. ## Choose Mode Ask only when context is unclear: > Hosted NVIDIA API or local Docker NIM? - Hosted: `https://health.api.nvidia.com/v1/biology/ipd/rfdiffusion/generate` - Local: `http://localhost:8000/biology/ipd/rfdiffusion/generate` Local inference paths do not include `/v1/`. Hosted requests use `Authorization: Bearer $NGC_API_KEY`. Supported local Docker startup uses `NGC_API_KEY` (or `NVIDIA_API_KEY` via the preflight) for registry login, entitlement checks, and first-run model downloads; pass it into the container with `-e NGC_API_KEY`. Local inference requests use no …
Read the whole file at its exact version.
How to install
mdr add nvidia/skills/rfdiffusion-nim@sha256:6c165c929d1bd8afThe line at the top of this page pins the label git:20261001.3ec135c, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.
[](https://markdownregistry.com/a/art_qll5nsgfyptaolr7)
4 badge image fetches in 30 days. What the badge shows.
Versions
The registry has recorded 1 version of this file, committed on Oct 1, 2026.
Audit of the latest version
- pass: Frontmatter block present
- pass: Frontmatter declares a name
- pass: Frontmatter declares a description
- pass: Size between 200 bytes and 200 KB (5374 bytes)
- pass: No zero-width or bidi control characters
- pass: No instruction hidden inside an HTML comment
- pass: No link to an exfiltration or paste host
- pass: No credential-shaped string
- pass: No instruction to send local credentials anywhere
- pass: No text hidden with inline styles
- pass: No prompt-injection phrasing
- pass: No curl or wget piped into a shell
- pass: No recursive delete of root, home or parent
- pass: No instruction to read or print local credentials
- pass: No base64 blob over 200 characters
- pass: No link to a raw IP address
- pass: No script tag
Source
nvidia/skills · 3,871 stars · license Apache-2.0 · pushed 2026-11-05 · branch main
API
GET https://markdownregistry.com/api/v1/artifacts/art_qll5nsgfyptaolr7 GET https://markdownregistry.com/api/v1/resolve?ref=nvidia/skills/rfdiffusion-nim GET https://markdownregistry.com/api/v1/blob/6c165c929d1bd8afc3f0674899ff534a175f283aae61b3e9c296d8f2e3076a19
Your AI assistant does the legwork. You hear about the deals worth your word. Hand yours the standing instructions at modelranch.com and it joins the network that reads files like this one.
Guides: the SKILL.md format and its required fields · what to check before you install a skill · how to pin a skill to an exact version · where to find agent skills · keeping a team on the same skills · which agent file does what.