openfold3-nim SKILL.md skillA

openfold3-nim from nvidia/skills is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.

Install it, pinned
mdr add nvidia/skills/openfold3-nim@git:20261001.2390ad9

Pins git:20261001.2390ad9 in mdr.lock. Pin the fingerprint instead.

Audit grade
A, 17 of 17 checks passed
Kind
SKILL.md skill
Repository
nvidia/skills
Path
skills/bionemo-openfold3-nim/SKILL.md
Versions recorded
1
Latest version
git:20261001.2390ad9, committed Oct 1, 2026
Size
7,585 bytes
Repository stars
3,871
License
Apache-2.0

Use this skill for OpenFold3, NVIDIA's BioNeMo NIM microservice for biomolecular structure prediction. Invoke whenever the user mentions OpenFold3 or needs protein, protein-ligand, protein-DNA/RNA, or multi-chain complex prediction with the hosted NVIDIA API or local Docker NIM. Covers endpoint choice, auth, request payloads, output artifacts, confidence scores, and local container setup.

Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.

What the file says

# OpenFold3 NIM

Predict biomolecular structures with OpenFold3. It supports proteins, DNA, RNA,
small-molecule ligands, and multi-entity assemblies. Use this guide for
basic hosted and local NIM use; load supplemental files only when the task needs
deeper context:

- `references/api.md`: exact endpoints, schemas, Docker flags, response fields.
- `references/science.md`: purpose, strengths, limitations, and model handoffs.
- `references/parameters.md`: molecule fields, MSAs, templates, samples, tuning.
- `references/validation.md`: artifact checks and scientific sanity checks.
- `references/examples.md`: compact hosted and local request patterns.

## Choose Mode

Ask only when context is unclear:

> Hosted NVIDIA API or local Docker NIM?

- Hosted URL: `https://health.api.nvidia.com/v1/biology/openfold/openfold3/predict`
- Local URL: `http://localhost:8000/biology/openfold/openfold3/predict`
- Local readiness: `http://localhost:8000/v1/health/ready`

Mode difference: the local prediction path has no `/v1/` prefix. Hosted requests use `Authorization: Bearer $NGC_API_KEY`. Supported local Docker
startup uses `NGC_API_KEY` (or `NVIDIA_API_KEY` via the preflight) for
…

Read the whole file at its exact version.

How to install

The exact contents, by fingerprint
mdr add nvidia/skills/openfold3-nim@sha256:a40a840c8542331e

The line at the top of this page pins the label git:20261001.2390ad9, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.

Badge

mdr badge

[![mdr](https://markdownregistry.com/badge/art_znopryoz5kh4xfyj.svg)](https://markdownregistry.com/a/art_znopryoz5kh4xfyj)

3 badge image fetches in 30 days. What the badge shows.

Versions

The registry has recorded 1 version of this file, committed on Oct 1, 2026.

versioncommittedcommitsizeaudit
git:20261001.2390ad9 latest2026-10-01 2390ad9 7,585 BA view

Audit of the latest version

A  17 of 17 checks passed. Fixed automatic checks with no AI involved, so the same checks give the same answer every run.
  • pass: Frontmatter block present
  • pass: Frontmatter declares a name
  • pass: Frontmatter declares a description
  • pass: Size between 200 bytes and 200 KB (7585 bytes)
  • pass: No zero-width or bidi control characters
  • pass: No instruction hidden inside an HTML comment
  • pass: No link to an exfiltration or paste host
  • pass: No credential-shaped string
  • pass: No instruction to send local credentials anywhere
  • pass: No text hidden with inline styles
  • pass: No prompt-injection phrasing
  • pass: No curl or wget piped into a shell
  • pass: No recursive delete of root, home or parent
  • pass: No instruction to read or print local credentials
  • pass: No base64 blob over 200 characters
  • pass: No link to a raw IP address
  • pass: No script tag

Source

GitHub

nvidia/skills · 3,871 stars · license Apache-2.0 · pushed 2026-11-05 · branch main

API

GET https://markdownregistry.com/api/v1/artifacts/art_znopryoz5kh4xfyj
GET https://markdownregistry.com/api/v1/resolve?ref=nvidia/skills/openfold3-nim
GET https://markdownregistry.com/api/v1/blob/a40a840c8542331ed3e9e08d9390bf9b88e6f9d3c46426cc2d07be67a899c2a6

Your AI assistant does the legwork. You hear about the deals worth your word. Hand yours the standing instructions at modelranch.com and it joins the network that reads files like this one.

Guides: the SKILL.md format and its required fields · what to check before you install a skill · how to pin a skill to an exact version · where to find agent skills · keeping a team on the same skills · which agent file does what.

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Every file in nvidia/skills

Other files named openfold3-nim

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openfold3-nim SKILL.md skill
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