msa-search-nim SKILL.md skillA

msa-search-nim from nvidia/skills is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.

Install it, pinned
mdr add nvidia/skills/msa-search-nim@git:20261001.b78d9ad

Pins git:20261001.b78d9ad in mdr.lock. Pin the fingerprint instead.

Audit grade
A, 17 of 17 checks passed
Kind
SKILL.md skill
Repository
nvidia/skills
Path
skills/bionemo-msa-search-nim/SKILL.md
Versions recorded
1
Latest version
git:20261001.b78d9ad, committed Oct 1, 2026
Size
18,248 bytes
Repository stars
3,871
License
Apache-2.0

Generate multiple sequence alignments (MSAs) for protein sequences using the ColabFold MSA-Search NIM. Use for homolog search, UniRef30/ColabFold env searches, A3M or FASTA alignments, paired MSA search for complexes, PDB70 structural templates, hosted NVIDIA API calls, or local Docker deployment. For local deployment, download the databases in parallel with aria2c and launch via NIM_MODEL_NAME (the recommended default fast path, ~14 min vs over 80 min for the built-in downloader); a plain…

Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.

What the file says

# MSA-Search NIM

Generate protein MSAs with GPU-accelerated MMSeqs2. Use this guide for
first-pass hosted/local usage; load supplemental files only when needed:

- `references/api.md`: exact endpoints, schemas, Docker flags, response fields.
- `references/science.md`: MSA purpose, pairing/templates, limits, handoffs.
- `references/parameters.md`: database, pairing, depth, and template tuning.
- `references/validation.md`: alignment, template, and artifact checks.
- `references/examples.md`: compact hosted/local request patterns.

## Choose Mode And Endpoint

Ask only when context is unclear:

> Hosted NVIDIA API or local Docker NIM?

- Hosted standard MSA: `https://health.api.nvidia.com/v1/biology/colabfold/msa-search/predict`
- Hosted paired MSA: `https://health.api.nvidia.com/v1/biology/colabfold/msa-search/paired/predict`
- Local standard MSA: `http://localhost:8000/biology/colabfold/msa-search/predict`
- Local paired MSA: `http://localhost:8000/biology/colabfold/msa-search/paired/predict`
- Local templates: `http://localhost:8000/biology/colabfold/msa-search/structure-templates/predict`
…

Read the whole file at its exact version.

How to install

The exact contents, by fingerprint
mdr add nvidia/skills/msa-search-nim@sha256:3d42c5136c5da1bc

The line at the top of this page pins the label git:20261001.b78d9ad, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.

Badge

mdr badge

[![mdr](https://markdownregistry.com/badge/art_2swxg2yvfgl4nc3e.svg)](https://markdownregistry.com/a/art_2swxg2yvfgl4nc3e)

2 badge image fetches in 30 days. What the badge shows.

Versions

The registry has recorded 1 version of this file, committed on Oct 1, 2026.

versioncommittedcommitsizeaudit
git:20261001.b78d9ad latest2026-10-01 b78d9ad 18,248 BA view

Audit of the latest version

A  17 of 17 checks passed. Fixed automatic checks with no AI involved, so the same checks give the same answer every run.
  • pass: Frontmatter block present
  • pass: Frontmatter declares a name
  • pass: Frontmatter declares a description
  • pass: Size between 200 bytes and 200 KB (18248 bytes)
  • pass: No zero-width or bidi control characters
  • pass: No instruction hidden inside an HTML comment
  • pass: No link to an exfiltration or paste host
  • pass: No credential-shaped string
  • pass: No instruction to send local credentials anywhere
  • pass: No text hidden with inline styles
  • pass: No prompt-injection phrasing
  • pass: No curl or wget piped into a shell
  • pass: No recursive delete of root, home or parent
  • pass: No instruction to read or print local credentials
  • pass: No base64 blob over 200 characters
  • pass: No link to a raw IP address
  • pass: No script tag

Source

GitHub

nvidia/skills · 3,871 stars · license Apache-2.0 · pushed 2026-11-05 · branch main

API

GET https://markdownregistry.com/api/v1/artifacts/art_2swxg2yvfgl4nc3e
GET https://markdownregistry.com/api/v1/resolve?ref=nvidia/skills/msa-search-nim
GET https://markdownregistry.com/api/v1/blob/3d42c5136c5da1bce8862e67fea25740958c7daba1f27a1c612695ac4dd03062

Your AI assistant does the legwork. You hear about the deals worth your word. Hand yours the standing instructions at modelranch.com and it joins the network that reads files like this one.

Guides: the SKILL.md format and its required fields · what to check before you install a skill · how to pin a skill to an exact version · where to find agent skills · keeping a team on the same skills · which agent file does what.

More from nvidia/skills

nvidia-skill-finder SKILL.md skill
nvidia/skills · plugins/nvidia-skills/skills/nvidia-skill-finder/SKILL.md · Use for NVIDIA-related requests where an NVIDIA skill might help, even if the user did not ask for a skill. Trigger on…
git:20261001.4aa3fd2 · audit A · 3,871 stars
accelerated-computing-cudf SKILL.md skill
nvidia/skills · skills/accelerated-computing-cudf/SKILL.md · Official NVIDIA-authored guidance for NVIDIA cuDF GPU DataFrames, pandas acceleration, dask-cuDF, ETL, joins, groupby…
git:20261015.7efb297 · audit A · 3,871 stars
aiq-deploy SKILL.md skill
nvidia/skills · skills/aiq-deploy/SKILL.md · Use when asked to install, deploy, run, validate, troubleshoot, or stop NVIDIA AI-Q Blueprint infrastructure.
v2.1.0 · audit A · 3,871 stars
aiq-research SKILL.md skill
nvidia/skills · skills/aiq-research/SKILL.md · Use when asked to run deep research or AI-Q research through a reachable NVIDIA AI-Q Blueprint backend.
v2.1.0 · audit A · 3,871 stars
ambient-healthcare-agent-with-nemotron-voice-agent SKILL.md skill
nvidia/skills · skills/ambient-healthcare-agent-with-nemotron-voice-agent/SKILL.md · Customize NVIDIA Nemotron Voice Agent's Generic Pipecat example for healthcare appointment, five-field patient intake…
v1.0.0 · audit B · 3,871 stars
amc-run-rtsp-calibration SKILL.md skill
nvidia/skills · skills/amc-run-rtsp-calibration/SKILL.md · Calibrate a new dataset from live RTSP camera streams via the AutoMagicCalib REST API. Use when the user provides RTSP…
v1.0.0 · audit B · 3,871 stars
amc-run-sample-calibration SKILL.md skill
nvidia/skills · skills/amc-run-sample-calibration/SKILL.md · Run end-to-end calibration on the shipped sample dataset (sdg_08_2_sample_data_010926.zip) against a running AMC…
v1.0.0 · audit A · 3,871 stars
amc-run-video-calibration SKILL.md skill
nvidia/skills · skills/amc-run-video-calibration/SKILL.md · Calibrates pre-recorded `cam_*.mp4` datasets through the AutoMagicCalib REST API. Use for user-supplied local MP4s…
v1.0.0 · audit A · 3,871 stars
amc-setup-calibration-stack SKILL.md skill
nvidia/skills · skills/amc-setup-calibration-stack/SKILL.md · Launch AutoMagicCalib microservice and web UI from NGC release images via Docker Compose. Use when user says 'deploy…
v1.0.0 · audit A · 3,871 stars
boltz2-nim SKILL.md skill
nvidia/skills · skills/bionemo-boltz2-nim/SKILL.md · Use Boltz2 NIM for biomolecular structure prediction and binding affinity. Invoke for Boltz2, protein structures…
git:20261002.85ad857 · audit A · 3,871 stars
codonfm-embed SKILL.md skill
nvidia/skills · skills/bionemo-codonfm-embed/SKILL.md · Validate coding-sequence CSVs, extract public CodonFM/Encodon embeddings, and choose checkpoints for downstream…
git:20261009.329cfc6 · audit A · 3,871 stars
codonfm-finetune SKILL.md skill
nvidia/skills · skills/bionemo-codonfm-finetune/SKILL.md · Fine-tune public CodonFM Encodon checkpoints on labeled coding-sequence or coding-variant data using LoRA, head-only…
git:20261009.329cfc6 · audit A · 3,871 stars

Every file in nvidia/skills

Other files named msa-search-nim

msa-search-nim SKILL.md skill
nvidia-bionemo/bionemo-agent-toolkit · skills/bionemo-agent-toolkit/skills/msa-search-nim/SKILL.md · Generate multiple sequence alignments (MSAs) for protein sequences using the ColabFold MSA-Search NIM. Use for homolog…
git:20260930.58a950a · audit A · 503 stars
msa-search-nim SKILL.md skill
nvidia-bionemo/bionemo-agent-toolkit · nim-skills/msa-search-nim/SKILL.md · Generate multiple sequence alignments (MSAs) for protein sequences using the ColabFold MSA-Search NIM. Use for homolog…
git:20260930.58a950a · audit A · 503 stars

Browse by kind, by grade A, or by owner.