msa-search-nim SKILL.md skillA

This file is byte-identical to the first copy the registry indexed, one of 3 indexed copies. Same content hash, so the same checks give both the same grade.

msa-search-nim from nvidia-bionemo/bionemo-agent-toolkit is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.

Install it, pinned
mdr add nvidia-bionemo/bionemo-agent-toolkit/msa-search-nim@git:20260930.58a950a

Pins git:20260930.58a950a in mdr.lock. Pin the fingerprint instead.

Audit grade
A, 17 of 17 checks passed
Kind
SKILL.md skill
Repository
nvidia-bionemo/bionemo-agent-toolkit
Path
skills/bionemo-agent-toolkit/skills/msa-search-nim/SKILL.md
Versions recorded
2
Latest version
git:20260930.58a950a, committed Sep 30, 2026
First version recorded
Aug 25, 2026
Size
18,248 bytes
Repository stars
503
License
a license file GitHub does not identify

Generate multiple sequence alignments (MSAs) for protein sequences using the ColabFold MSA-Search NIM. Use for homolog search, UniRef30/ColabFold env searches, A3M or FASTA alignments, paired MSA search for complexes, PDB70 structural templates, hosted NVIDIA API calls, or local Docker deployment. For local deployment, download the databases in parallel with aria2c and launch via NIM_MODEL_NAME (the recommended default fast path, ~14 min vs over 80 min for the built-in downloader); a plain…

Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.

What the file says

# MSA-Search NIM

Generate protein MSAs with GPU-accelerated MMSeqs2. Use this guide for
first-pass hosted/local usage; load supplemental files only when needed:

- `references/api.md`: exact endpoints, schemas, Docker flags, response fields.
- `references/science.md`: MSA purpose, pairing/templates, limits, handoffs.
- `references/parameters.md`: database, pairing, depth, and template tuning.
- `references/validation.md`: alignment, template, and artifact checks.
- `references/examples.md`: compact hosted/local request patterns.

## Choose Mode And Endpoint

Ask only when context is unclear:

> Hosted NVIDIA API or local Docker NIM?

- Hosted standard MSA: `https://health.api.nvidia.com/v1/biology/colabfold/msa-search/predict`
- Hosted paired MSA: `https://health.api.nvidia.com/v1/biology/colabfold/msa-search/paired/predict`
- Local standard MSA: `http://localhost:8000/biology/colabfold/msa-search/predict`
- Local paired MSA: `http://localhost:8000/biology/colabfold/msa-search/paired/predict`
- Local templates: `http://localhost:8000/biology/colabfold/msa-search/structure-templates/predict`
…

Read the whole file at its exact version.

How to install

The exact contents, by fingerprint
mdr add nvidia-bionemo/bionemo-agent-toolkit/msa-search-nim@sha256:3d42c5136c5da1bc

The line at the top of this page pins the label git:20260930.58a950a, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.

Badge

mdr badge

[![mdr](https://markdownregistry.com/badge/art_c4h6viltx73rwrxu.svg)](https://markdownregistry.com/a/art_c4h6viltx73rwrxu)

3 badge image fetches in 30 days. What the badge shows.

Versions

The registry has recorded 2 versions of this file, between Aug 25, 2026 and Sep 30, 2026, about one every 37 days.

versioncommittedcommitsizeaudit
git:20260930.58a950a latest2026-09-30 58a950a 18,248 BA view · diff
git:20260825.0e67a612026-08-25 0e67a61 16,808 BA view

Audit of the latest version

A  17 of 17 checks passed. Fixed automatic checks with no AI involved, so the same checks give the same answer every run.
  • pass: Frontmatter block present
  • pass: Frontmatter declares a name
  • pass: Frontmatter declares a description
  • pass: Size between 200 bytes and 200 KB (18248 bytes)
  • pass: No zero-width or bidi control characters
  • pass: No instruction hidden inside an HTML comment
  • pass: No link to an exfiltration or paste host
  • pass: No credential-shaped string
  • pass: No instruction to send local credentials anywhere
  • pass: No text hidden with inline styles
  • pass: No prompt-injection phrasing
  • pass: No curl or wget piped into a shell
  • pass: No recursive delete of root, home or parent
  • pass: No instruction to read or print local credentials
  • pass: No base64 blob over 200 characters
  • pass: No link to a raw IP address
  • pass: No script tag

Source

GitHub

nvidia-bionemo/bionemo-agent-toolkit · 503 stars · license a license file GitHub does not identify · pushed 2026-11-05 · branch main

API

GET https://markdownregistry.com/api/v1/artifacts/art_c4h6viltx73rwrxu
GET https://markdownregistry.com/api/v1/resolve?ref=nvidia-bionemo/bionemo-agent-toolkit/msa-search-nim
GET https://markdownregistry.com/api/v1/blob/3d42c5136c5da1bce8862e67fea25740958c7daba1f27a1c612695ac4dd03062

Your AI assistant does the legwork. You hear about the deals worth your word. Hand yours the standing instructions at modelranch.com and it joins the network that reads files like this one.

Guides: the SKILL.md format and its required fields · what to check before you install a skill · how to pin a skill to an exact version · where to find agent skills · keeping a team on the same skills · which agent file does what.

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Every file in nvidia-bionemo/bionemo-agent-toolkit

Other files named msa-search-nim

msa-search-nim SKILL.md skill
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msa-search-nim SKILL.md skill
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