boltz2-nim SKILL.md skillA
This file is byte-identical to the first copy the registry indexed, one of 3 indexed copies. Same content hash, so the same checks give both the same grade.
boltz2-nim from nvidia-bionemo/bionemo-agent-toolkit is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.
mdr add nvidia-bionemo/bionemo-agent-toolkit/boltz2-nim@git:20261001.237ee05Pins git:20261001.237ee05 in mdr.lock. Pin the fingerprint instead.
- Audit grade
- A, 17 of 17 checks passed
- Kind
- SKILL.md skill
- Repository
- nvidia-bionemo/bionemo-agent-toolkit
- Path
skills/bionemo-agent-toolkit/skills/boltz2-nim/SKILL.md- Versions recorded
- 2
- Latest version
- git:20261001.237ee05, committed Oct 1, 2026
- First version recorded
- Aug 25, 2026
- Size
- 5,513 bytes
- Repository stars
- 503
- License
- a license file GitHub does not identify
Use Boltz2 NIM for biomolecular structure prediction and binding affinity. Invoke for Boltz2, protein structures, protein-ligand/DNA/RNA complexes, SMILES or CCD ligands, pIC50/IC50 affinity scoring, mmCIF output, hosted NVIDIA API calls, or local Docker deployment.
Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.
What the file says
# Boltz2 NIM
Predict biomolecular structures and optional ligand affinity. Use this
guide for first-pass hosted/local usage; load supplemental files only when
needed:
- `references/api.md`: exact endpoints, schemas, Docker flags, response fields.
- `references/science.md`: purpose, strengths, limitations, and handoffs.
- `references/parameters.md`: prediction, sampling, MSA, template, affinity tuning.
- `references/validation.md`: mmCIF, confidence, affinity, and chemistry checks.
- `references/examples.md`: compact hosted/local payload patterns.
## Instructions
Read credentials from the environment only when needed. Check presence with
`bool(os.getenv("NGC_API_KEY"))`; keep key values and Authorization headers out of
terminal output, logs, saved artifacts, and the final response. Avoid environment
dumps when diagnosing authentication. If the hosted key is absent, report the
missing variable before submitting a request.
### Choose Mode
Ask only when context is unclear:
> Hosted NVIDIA API or local Docker NIM?
- Hosted: `https://health.api.nvidia.com/v1/biology/mit/boltz2/predict`
- Local: `http://localhost:8000/biology/mit/boltz2/predict`
…Read the whole file at its exact version.
How to install
mdr add nvidia-bionemo/bionemo-agent-toolkit/boltz2-nim@sha256:afd96c38f832ab5bThe line at the top of this page pins the label git:20261001.237ee05, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.
[](https://markdownregistry.com/a/art_3ovasdkkr2u2ype4)
3 badge image fetches in 30 days. What the badge shows.
Versions
The registry has recorded 2 versions of this file, between Aug 25, 2026 and Oct 1, 2026, about one every 38 days.
| version | committed | commit | size | audit | |
|---|---|---|---|---|---|
| git:20261001.237ee05 latest | 2026-10-01 | 237ee05 | 5,513 B | A | view · diff |
| git:20260825.0e67a61 | 2026-08-25 | 0e67a61 | 5,004 B | A | view |
Audit of the latest version
- pass: Frontmatter block present
- pass: Frontmatter declares a name
- pass: Frontmatter declares a description
- pass: Size between 200 bytes and 200 KB (5513 bytes)
- pass: No zero-width or bidi control characters
- pass: No instruction hidden inside an HTML comment
- pass: No link to an exfiltration or paste host
- pass: No credential-shaped string
- pass: No instruction to send local credentials anywhere
- pass: No text hidden with inline styles
- pass: No prompt-injection phrasing
- pass: No curl or wget piped into a shell
- pass: No recursive delete of root, home or parent
- pass: No instruction to read or print local credentials
- pass: No base64 blob over 200 characters
- pass: No link to a raw IP address
- pass: No script tag
Source
nvidia-bionemo/bionemo-agent-toolkit · 503 stars · license a license file GitHub does not identify · pushed 2026-11-05 · branch main
API
GET https://markdownregistry.com/api/v1/artifacts/art_3ovasdkkr2u2ype4 GET https://markdownregistry.com/api/v1/resolve?ref=nvidia-bionemo/bionemo-agent-toolkit/boltz2-nim GET https://markdownregistry.com/api/v1/blob/afd96c38f832ab5b67b7b9f0ff967e387639c73676979bfe7cd9b34f20d55e90
Your AI assistant does the legwork. You hear about the deals worth your word. Hand yours the standing instructions at modelranch.com and it joins the network that reads files like this one.
Guides: the SKILL.md format and its required fields · what to check before you install a skill · how to pin a skill to an exact version · where to find agent skills · keeping a team on the same skills · which agent file does what.
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