rfd4-proteina-generate SKILL.md skillA
rfd4-proteina-generate from nvidia-bionemo/bionemo-agent-toolkit is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.
mdr add nvidia-bionemo/bionemo-agent-toolkit/rfd4-proteina-generate@git:20261020.65f97c4Pins git:20261020.65f97c4 in mdr.lock. Pin the fingerprint instead.
- Audit grade
- A, 17 of 17 checks passed
- Kind
- SKILL.md skill
- Repository
- nvidia-bionemo/bionemo-agent-toolkit
- Path
skills/bionemo-agent-toolkit/skills/rfd4-proteina-generate/SKILL.md- Versions recorded
- 1
- Latest version
- git:20261020.65f97c4, committed Oct 20, 2026
- Size
- 10,675 bytes
- Repository stars
- 503
- License
- a license file GitHub does not identify
Use when generating RFD4-Proteina designs from annotated inputs with task, sampling, batch, and inline-metric choices.
Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.
What the file says
# RFD4-Proteína Generate ## Purpose Single-shot generation for RFD4-Proteína. One entry point drives every design task — unconditional monomers/complexes, folding & inverse folding, motif scaffolding, enzyme design, small-molecule binders, protein binders, and DNA binders. The skill's job is to **route** the request to the right example input and the right overrides, then run one command. Deep input construction, reward-guided search, and oracle metrics live in sibling skills; this skill points at them. Run everything from the repository root (the directory containing `.project-root`). All model arguments are Hydra `key=value`, **never** `--key value`. ## Prerequisites A model environment that passes setup preflight, supported GPU, checkpoints, and a validated annotated input or benchmark example. Use the user-selected model checkout at `RFPROTEINA_ROOT` for model commands, configs, and upstream manuals. This catalog contains the skills, not that checkout. In helper examples, resolve `open-models-skills/rfd4-proteina/<name>/...` to its absolute installed path when the catalog and model checkout are separate. ## Inputs …
Read the whole file at its exact version.
How to install
mdr add nvidia-bionemo/bionemo-agent-toolkit/rfd4-proteina-generate@sha256:e16d94d7503c86e9The line at the top of this page pins the label git:20261020.65f97c4, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.
[](https://markdownregistry.com/a/art_4qmxkkqaw76ju6si)
3 badge image fetches in 30 days. What the badge shows.
Versions
The registry has recorded 1 version of this file, committed on Oct 20, 2026.
Audit of the latest version
- pass: Frontmatter block present
- pass: Frontmatter declares a name
- pass: Frontmatter declares a description
- pass: Size between 200 bytes and 200 KB (10675 bytes)
- pass: No zero-width or bidi control characters
- pass: No instruction hidden inside an HTML comment
- pass: No link to an exfiltration or paste host
- pass: No credential-shaped string
- pass: No instruction to send local credentials anywhere
- pass: No text hidden with inline styles
- pass: No prompt-injection phrasing
- pass: No curl or wget piped into a shell
- pass: No recursive delete of root, home or parent
- pass: No instruction to read or print local credentials
- pass: No base64 blob over 200 characters
- pass: No link to a raw IP address
- pass: No script tag
Source
nvidia-bionemo/bionemo-agent-toolkit · 503 stars · license a license file GitHub does not identify · pushed 2026-11-05 · branch main
API
GET https://markdownregistry.com/api/v1/artifacts/art_4qmxkkqaw76ju6si GET https://markdownregistry.com/api/v1/resolve?ref=nvidia-bionemo/bionemo-agent-toolkit/rfd4-proteina-generate GET https://markdownregistry.com/api/v1/blob/e16d94d7503c86e90a6c84514df638167b2be1a6e21aba85d72f47e98c888c74
Your AI assistant does the legwork. You hear about the deals worth your word. Hand yours the standing instructions at modelranch.com and it joins the network that reads files like this one.
Guides: the SKILL.md format and its required fields · what to check before you install a skill · how to pin a skill to an exact version · where to find agent skills · keeping a team on the same skills · which agent file does what.
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