opentrons-magnetic-block SKILL.md skillA

opentrons-magnetic-block from jkitchin/knowhow is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.

Install it, pinned
mdr add jkitchin/knowhow/opentrons-magnetic-block@git:20251129.b0f1718

Pins git:20251129.b0f1718 in mdr.lock. Pin the fingerprint instead.

Audit grade
A, 17 of 17 checks passed
Kind
SKILL.md skill
Repository
jkitchin/knowhow
Path
skills/laboratory/opentrons-magnetic-block/SKILL.md
Versions recorded
1
Latest version
git:20251129.b0f1718, committed Nov 29, 2025
Size
21,314 bytes
Repository stars
42
License
MIT

Opentrons Magnetic Block for Flex - unpowered magnetic bead separation using gripper-based labware movement with high-strength neodymium magnets for DNA/RNA purification, immunoprecipitation, and bead-based workflows.

Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.

What the file says

# Opentrons Magnetic Block

## Overview

The **Opentrons Magnetic Block** is an unpowered, 96-well magnetic separator exclusively for Opentrons Flex. It uses high-strength neodymium magnets to pull magnetic beads to the side of wells, enabling supernatant removal for DNA/RNA purification, protein cleanup, immunoprecipitation, and other bead-based separation protocols.

**Core value:** Automate magnetic bead-based purification workflows without manual plate transfers. Combine gripper-based plate movement with magnetic separation for fully automated DNA extraction, PCR cleanup, and bead-based assays.

**Platform:** Opentrons Flex only (not compatible with OT-2)

## When to Use

Use the Magnetic Block skill when:
- Performing DNA/RNA extraction with magnetic beads
- PCR product cleanup (AMPure, SPRIselect beads)
- Magnetic bead-based library preparation (NGS)
- Protein purification or immunoprecipitation with magnetic beads
- Cell sorting or enrichment with magnetic particles
- Any protocol requiring magnetic bead separation

**Don't use when:**
- Working with OT-2 robot (Magnetic Block is Flex-only)
- Need vertical bead movement within solution (block only pulls to side)
…

Read the whole file at its exact version.

How to install

The exact contents, by fingerprint
mdr add jkitchin/knowhow/opentrons-magnetic-block@sha256:c41774579e3699ea

The line at the top of this page pins the label git:20251129.b0f1718, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.

Badge

mdr badge

[![mdr](https://markdownregistry.com/badge/art_7uudnhz6dhpqokn3.svg)](https://markdownregistry.com/a/art_7uudnhz6dhpqokn3)

0 badge image fetches in 30 days. What the badge shows.

Versions

The registry has recorded 1 version of this file, committed on Nov 29, 2025.

versioncommittedcommitsizeaudit
git:20251129.b0f1718 latest2025-11-29 b0f1718 21,314 BA view

Audit of the latest version

A  17 of 17 checks passed. Fixed automatic checks with no AI involved, so the same checks give the same answer every run.
  • pass: Frontmatter block present
  • pass: Frontmatter declares a name
  • pass: Frontmatter declares a description
  • pass: Size between 200 bytes and 200 KB (21314 bytes)
  • pass: No zero-width or bidi control characters
  • pass: No instruction hidden inside an HTML comment
  • pass: No link to an exfiltration or paste host
  • pass: No credential-shaped string
  • pass: No instruction to send local credentials anywhere
  • pass: No text hidden with inline styles
  • pass: No prompt-injection phrasing
  • pass: No curl or wget piped into a shell
  • pass: No recursive delete of root, home or parent
  • pass: No instruction to read or print local credentials
  • pass: No base64 blob over 200 characters
  • pass: No link to a raw IP address
  • pass: No script tag

Source

GitHub

jkitchin/knowhow · 42 stars · license MIT · pushed 2026-11-02 · branch main

API

GET https://markdownregistry.com/api/v1/artifacts/art_7uudnhz6dhpqokn3
GET https://markdownregistry.com/api/v1/resolve?ref=jkitchin/knowhow/opentrons-magnetic-block
GET https://markdownregistry.com/api/v1/blob/c41774579e3699ea5dc06352656e4b3dcc92d4dd121ba52cdf89476f31c2fab7

Your AI assistant does the legwork. You hear about the deals worth your word. Hand yours the standing instructions at modelranch.com and it joins the network that reads files like this one.

Guides: the SKILL.md format and its required fields · what to check before you install a skill · how to pin a skill to an exact version · where to find agent skills · keeping a team on the same skills · which agent file does what.

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