archs4-database SKILL.md skillA

This file is byte-identical to the first copy the registry indexed. Same content hash, so the same checks give both the same grade.

archs4-database from fridrichmethod/awesome-skills is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.

Install it, pinned
mdr add fridrichmethod/awesome-skills/archs4-database@git:20260830.b77323f

Pins git:20260830.b77323f in mdr.lock. Pin the fingerprint instead.

Audit grade
A, 17 of 17 checks passed
Kind
SKILL.md skill
Repository
fridrichmethod/awesome-skills
Path
skills/archs4-database/SKILL.md
Versions recorded
2
Latest version
git:20260830.b77323f, committed Aug 30, 2026
First version recorded
May 17, 2026
Size
26,447 bytes
Repository stars
15
License
a license file GitHub does not identify

Query ARCHS4 REST API for uniformly processed RNA-seq expression, tissue patterns, co-expression across 1M+ human/mouse samples. Retrieve z-scores, co-expressed genes, samples by metadata, HDF5 matrices. For variant population genetics use gnomad-database; for pathway enrichment use gget-genomic-databases (Enrichr).

Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.

What the file says

# ARCHS4 Database

## Overview

ARCHS4 (All RNA-seq and ChIP-seq Sample and Signature Search) is a resource of uniformly aligned and processed human and mouse RNA-seq data from NCBI GEO and SRA, covering 1 million+ samples. The REST API at `https://maayanlab.cloud/archs4/api/` provides gene-level expression profiles, z-score normalized tissue expression, co-expression networks, and sample metadata search — all without authentication. Large-scale bulk queries can also use the downloadable HDF5 expression matrices.

## When to Use

- Retrieving tissue-specific or cell-type-specific expression z-scores for a gene of interest across hundreds of tissue types
- Finding genes co-expressed with a query gene (co-expression network construction or guilt-by-association analysis)
- Searching for RNA-seq samples by tissue, disease, or metadata keyword to identify candidate datasets for reanalysis
- Comparing expression profiles of multiple genes across tissues to prioritize candidates for wet-lab follow-up
- Accessing uniformly processed gene expression matrices (HDF5 format) for large-scale cross-study analysis
…

Read the whole file at its exact version.

How to install

The exact contents, by fingerprint
mdr add fridrichmethod/awesome-skills/archs4-database@sha256:885f83e0664d091f

The line at the top of this page pins the label git:20260830.b77323f, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.

Badge

mdr badge

[![mdr](https://markdownregistry.com/badge/art_iptouanqfhyf2ksm.svg)](https://markdownregistry.com/a/art_iptouanqfhyf2ksm)

0 badge image fetches in 30 days. What the badge shows.

Versions

The registry has recorded 2 versions of this file, between May 17, 2026 and Aug 30, 2026, about one every 105 days.

versioncommittedcommitsizeaudit
git:20260830.b77323f latest2026-08-30 b77323f 26,447 BA view · diff
git:20260517.81511a72026-05-17 81511a7 27,246 BA view

Audit of the latest version

A  17 of 17 checks passed. Fixed automatic checks with no AI involved, so the same checks give the same answer every run.
  • pass: Frontmatter block present
  • pass: Frontmatter declares a name
  • pass: Frontmatter declares a description
  • pass: Size between 200 bytes and 200 KB (26447 bytes)
  • pass: No zero-width or bidi control characters
  • pass: No instruction hidden inside an HTML comment
  • pass: No link to an exfiltration or paste host
  • pass: No credential-shaped string
  • pass: No instruction to send local credentials anywhere
  • pass: No text hidden with inline styles
  • pass: No prompt-injection phrasing
  • pass: No curl or wget piped into a shell
  • pass: No recursive delete of root, home or parent
  • pass: No instruction to read or print local credentials
  • pass: No base64 blob over 200 characters
  • pass: No link to a raw IP address
  • pass: No script tag

Source

GitHub

fridrichmethod/awesome-skills · 15 stars · license a license file GitHub does not identify · pushed 2026-10-18 · branch main

API

GET https://markdownregistry.com/api/v1/artifacts/art_iptouanqfhyf2ksm
GET https://markdownregistry.com/api/v1/resolve?ref=fridrichmethod/awesome-skills/archs4-database
GET https://markdownregistry.com/api/v1/blob/885f83e0664d091f8b2ca991aa781fd084c158428f990d5d71634020d11c59bd

Your AI assistant does the legwork. You hear about the deals worth your word. Hand yours the standing instructions at modelranch.com and it joins the network that reads files like this one.

Guides: the SKILL.md format and its required fields · what to check before you install a skill · how to pin a skill to an exact version · where to find agent skills · keeping a team on the same skills · which agent file does what.

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Every file in fridrichmethod/awesome-skills

Other files named archs4-database

archs4-database SKILL.md skill
jaechang-hits/sciagent-skills · skills/genomics-bioinformatics/databases/archs4-database/SKILL.md · Query ARCHS4 REST API for uniformly processed RNA-seq expression, tissue patterns, co-expression across 1M+ human/mouse…
git:20260827.cbbeb75 · audit A · 381 stars

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