bioinformatics-technician SKILL.md skillA
bioinformatics-technician from wonsukchoi/domain-experts is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.
mdr add wonsukchoi/domain-experts/bioinformatics-technician@git:20260707.fa77dcePins git:20260707.fa77dce in mdr.lock. Pin the fingerprint instead.
- Audit grade
- A, 17 of 17 checks passed
- Kind
- SKILL.md skill
- Repository
- wonsukchoi/domain-experts
- Path
roles/bioinformatics-technician/SKILL.md- Versions recorded
- 1
- Latest version
- git:20260707.fa77dce, committed Jul 7, 2026
- Size
- 10,673 bytes
- Repository stars
- 25
- License
- MIT
Use when a task needs the judgment of a bioinformatics technician — running or QC-gating a next-generation sequencing pipeline, triaging a failed or borderline sequencing run, deciding whether a variant call set is clinically/research reportable, or writing a sample-level QC report.
Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.
What the file says
# Bioinformatics Technician ## Identity Runs and QC-gates established sequencing and variant-calling pipelines in a research core lab or clinical molecular diagnostics lab — executing GATK/DRAGEN-class workflows built by bioinformatics scientists, not designing new algorithms. Accountable for whether a sample's output is trustworthy enough to leave the lab, which means the real job is knowing which QC numbers are cosmetic and which ones invalidate the run. ## First-principles core 1. **A pipeline that completes without error is not the same as a pipeline that produced a usable answer.** Exit code 0 only means no software crash; coverage uniformity, contamination, and mapping quality are separate questions the pipeline doesn't ask itself. 2. **QC thresholds exist because a specific failure mode produces a specific signature.** Low mean depth with even distribution is a loading-concentration problem; low depth with a sawtooth pattern across the genome is a GC-bias or capture problem — same headline metric, different root cause and different fix. …
Read the whole file at its exact version.
How to install
mdr add wonsukchoi/domain-experts/bioinformatics-technician@sha256:63ba85f28ed54b7aThe line at the top of this page pins the label git:20260707.fa77dce, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.
[](https://markdownregistry.com/a/art_mzd7o34eaekgxzmy)
3 badge image fetches in 30 days. What the badge shows.
Versions
The registry has recorded 1 version of this file, committed on Jul 7, 2026.
Audit of the latest version
- pass: Frontmatter block present
- pass: Frontmatter declares a name
- pass: Frontmatter declares a description
- pass: Size between 200 bytes and 200 KB (10673 bytes)
- pass: No zero-width or bidi control characters
- pass: No instruction hidden inside an HTML comment
- pass: No link to an exfiltration or paste host
- pass: No credential-shaped string
- pass: No instruction to send local credentials anywhere
- pass: No text hidden with inline styles
- pass: No prompt-injection phrasing
- pass: No curl or wget piped into a shell
- pass: No recursive delete of root, home or parent
- pass: No instruction to read or print local credentials
- pass: No base64 blob over 200 characters
- pass: No link to a raw IP address
- pass: No script tag
Source
wonsukchoi/domain-experts · 25 stars · license MIT · pushed 2026-11-03 · branch main
API
GET https://markdownregistry.com/api/v1/artifacts/art_mzd7o34eaekgxzmy GET https://markdownregistry.com/api/v1/resolve?ref=wonsukchoi/domain-experts/bioinformatics-technician GET https://markdownregistry.com/api/v1/blob/63ba85f28ed54b7ad927486a002316653bda2ace8b7b5d75e681589096051b9b
Your AI assistant does the legwork. You hear about the deals worth your word. Hand yours the standing instructions at modelranch.com and it joins the network that reads files like this one.
Guides: the SKILL.md format and its required fields · what to check before you install a skill · how to pin a skill to an exact version · where to find agent skills · keeping a team on the same skills · which agent file does what.