marielynneblock/arcanum-artifex · skills/scientific/bindingdb-database/SKILL.md

bindingdb-database skillA

bindingdb-database is agent-read markdown (skill) from marielynneblock/arcanum-artifex: Query BindingDB for measured drug-target binding affinities (Ki, Kd, IC50, EC50). Search by target (UniProt ID), compound (SMILES/name), or pathogen. Essential for drug discovery, lead optimisation, polypharmacology analysis, and structure-activity relationship (SAR) studies..

Indexed from public GitHub and served as immutable, content-addressed versions. Install it pinned to an exact SHA-256 with the mdr CLI, and every file is verified against the hash recorded here before it reaches your agent. The deterministic audit below grades the latest version, and the same file always earns the same grade.

How to install

Latest version
mdr add marielynneblock/arcanum-artifex/bindingdb-database@git:20260710.0115f49
Exact content
mdr add marielynneblock/arcanum-artifex/bindingdb-database@sha256:2cfdee4ff80b21cc

Pin to a label to follow the author's releases, or to a sha256 to freeze the exact bytes forever. Either way the resolved hash is written to mdr.lock, and mdr install reproduces it on any machine.

Badge

mdr badge

[![mdr](https://markdownregistry.com/badge/art_vw6rerobegintzqy.svg)](https://markdownregistry.com/a/art_vw6rerobegintzqy)

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Versions

versioncommittedcommitsizeaudit
git:20260710.0115f49 latest2026-07-10 0115f49 12,069 BA view · diff
git:20260710.ffb34002026-07-10 ffb3400 12,069 BA view · diff
git:20260515.b861afb2026-05-15 b861afb 12,069 BA view · diff
git:20260406.05dff342026-04-06 05dff34 12,069 BA view

Audit of the latest version

A  17 of 17 checks passed. Deterministic, no model, same answer every run.
  • pass: Frontmatter block present
  • pass: Frontmatter declares a name
  • pass: Frontmatter declares a description
  • pass: Size between 200 bytes and 200 KB (12069 bytes)
  • pass: No zero-width or bidi control characters
  • pass: No instruction hidden inside an HTML comment
  • pass: No link to an exfiltration or paste host
  • pass: No credential-shaped string
  • pass: No instruction to send local credentials anywhere
  • pass: No text hidden with inline styles
  • pass: No prompt-injection phrasing
  • pass: No curl or wget piped into a shell
  • pass: No recursive delete of root, home or parent
  • pass: No instruction to read or print local credentials
  • pass: No base64 blob over 200 characters
  • pass: No link to a raw IP address
  • pass: No script tag

Source

GitHub

marielynneblock/arcanum-artifex · 4 stars · license none · pushed 2026-09-16 · branch main

API

GET https://markdownregistry.com/api/v1/artifacts/art_vw6rerobegintzqy
GET https://markdownregistry.com/api/v1/resolve?ref=marielynneblock/arcanum-artifex/bindingdb-database
GET https://markdownregistry.com/api/v1/blob/2cfdee4ff80b21cce84279e7687e159ff798242944a81d25712faa8082595fbf

Agents talk at modelranch.com: hand yours the instructions there and it joins the network that reads files like this one.