biochemist SKILL.md skillA
biochemist from wonsukchoi/domain-experts is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.
mdr add wonsukchoi/domain-experts/biochemist@git:20260707.1672850Pins git:20260707.1672850 in mdr.lock. Pin the fingerprint instead.
- Audit grade
- A, 17 of 17 checks passed
- Kind
- SKILL.md skill
- Repository
- wonsukchoi/domain-experts
- Path
roles/biochemist/SKILL.md- Versions recorded
- 1
- Latest version
- git:20260707.1672850, committed Jul 7, 2026
- Size
- 14,266 bytes
- Repository stars
- 25
- License
- MIT
Use when a task needs the judgment of a Biochemist — determining enzyme kinetics (Km/Vmax, inhibition mechanism) from rate data, choosing a structural-biology method (X-ray crystallography, cryo-EM, or NMR) for a target, designing or interpreting a binding assay (ITC, SPR, fluorescence polarization), or selecting a protein-purification strategy and diagnosing why a prep failed.
Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.
What the file says
# Biochemist (Enzyme Kinetics, Structural Biology, Protein Biochemistry) ## Identity A molecular/structural biochemist with 10+ years in an academic, biotech, or pharma research lab — characterizing how a protein works (kinetics, binding, structure) rather than what small molecule might modulate it (`chemist`'s domain) or which organism is present in a sample (`microbiologist`'s domain). Owns the protein: getting it pure and active, measuring what it actually does kinetically, and choosing the right window (crystallography, cryo-EM, NMR, or none of those) onto its structure. The defining tension: a beautifully executed kinetics assay or structure on a mishandled or partially denatured protein prep produces a precise, reproducible, wrong answer. ## First-principles core 1. **A kinetic parameter measured on impure or partially inactive protein is a property of the prep, not the enzyme.** Km and Vmax are only interpretable if the active-site concentration is known — a prep that's 60% active protein by mass gives a Vmax that's 60% of the true value and a Km that can shift if the inactive fraction competes for substrate or aggregates. …
Read the whole file at its exact version.
How to install
mdr add wonsukchoi/domain-experts/biochemist@sha256:bd57fbf954cfdb8eThe line at the top of this page pins the label git:20260707.1672850, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.
[](https://markdownregistry.com/a/art_xm57twxlsha5ctlq)
4 badge image fetches in 30 days. What the badge shows.
Versions
The registry has recorded 1 version of this file, committed on Jul 7, 2026.
Audit of the latest version
- pass: Frontmatter block present
- pass: Frontmatter declares a name
- pass: Frontmatter declares a description
- pass: Size between 200 bytes and 200 KB (14266 bytes)
- pass: No zero-width or bidi control characters
- pass: No instruction hidden inside an HTML comment
- pass: No link to an exfiltration or paste host
- pass: No credential-shaped string
- pass: No instruction to send local credentials anywhere
- pass: No text hidden with inline styles
- pass: No prompt-injection phrasing
- pass: No curl or wget piped into a shell
- pass: No recursive delete of root, home or parent
- pass: No instruction to read or print local credentials
- pass: No base64 blob over 200 characters
- pass: No link to a raw IP address
- pass: No script tag
Source
wonsukchoi/domain-experts · 25 stars · license MIT · pushed 2026-11-03 · branch main
API
GET https://markdownregistry.com/api/v1/artifacts/art_xm57twxlsha5ctlq GET https://markdownregistry.com/api/v1/resolve?ref=wonsukchoi/domain-experts/biochemist GET https://markdownregistry.com/api/v1/blob/bd57fbf954cfdb8ef8b091a32cc118620e6c11f8d9c433aa857e86ffe4adf506
Your AI assistant does the legwork. You hear about the deals worth your word. Hand yours the standing instructions at modelranch.com and it joins the network that reads files like this one.
Guides: the SKILL.md format and its required fields · what to check before you install a skill · how to pin a skill to an exact version · where to find agent skills · keeping a team on the same skills · which agent file does what.