interpro-database SKILL.md skillA

interpro-database from jaechang-hits/sciagent-skills is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.

Install it, pinned
mdr add jaechang-hits/sciagent-skills/interpro-database@git:20260522.6a6fd41

Pins git:20260522.6a6fd41 in mdr.lock. Pin the fingerprint instead.

Audit grade
A, 17 of 17 checks passed
Kind
SKILL.md skill
Repository
jaechang-hits/sciagent-skills
Path
skills/proteomics-protein-engineering/interpro-database/SKILL.md
Versions recorded
3
Latest version
git:20260522.6a6fd41, committed May 22, 2026
First version recorded
Feb 18, 2026
Size
30,318 bytes
Repository stars
381
License
a license file GitHub does not identify

Query InterPro REST API for protein domain architecture, family classification, and member-DB integration. Search entries, retrieve a protein's domains, list family members, get taxonomic distribution, link to PDB. Unifies Pfam, PANTHER, PIRSF, PRINTS, PROSITE, SMART, CDD, NCBIfam. Use uniprot-protein-database for sequences; pdb-database for 3D structures.

Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.

What the file says

# InterPro Database

## Overview

InterPro is the EBI's integrated protein family, domain, and functional site database. It consolidates signatures from 13 member databases (Pfam, PANTHER, PIRSF, PRINTS, PROSITE, SMART, CDD, NCBIfam, and others) into unified InterPro entries, each describing a homologous superfamily, domain, family, repeat, or conserved site. The REST API at `https://www.ebi.ac.uk/interpro/api/` is free and requires no authentication.

## When to Use

- Identifying all domains and families present in a protein by UniProt accession (domain architecture)
- Searching for proteins that contain a specific domain or belong to a specific family
- Finding the taxonomic distribution of organisms that encode a given domain or family
- Cross-linking a domain to experimental 3D structures in the PDB
- Checking which source databases (Pfam, PANTHER, SMART, etc.) cover an InterPro entry
- Discovering InterPro entries by keyword (e.g., "kinase domain") when you do not yet know the accession
- For protein sequence retrieval, functional annotations (GO, pathways, active sites), and ID mapping use `uniprot-protein-database`
…

Read the whole file at its exact version.

How to install

The exact contents, by fingerprint
mdr add jaechang-hits/sciagent-skills/interpro-database@sha256:19bd30336d78036f

The line at the top of this page pins the label git:20260522.6a6fd41, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.

Badge

mdr badge

[![mdr](https://markdownregistry.com/badge/art_6jjyj63lfzxih2uj.svg)](https://markdownregistry.com/a/art_6jjyj63lfzxih2uj)

2 badge image fetches in 30 days. What the badge shows.

Versions

The registry has recorded 3 versions of this file, between Feb 18, 2026 and May 22, 2026, about one every 46 days.

versioncommittedcommitsizeaudit
git:20260522.6a6fd41 latest2026-05-22 6a6fd41 30,318 BA view · diff
git:20260428.81ea2d22026-04-28 81ea2d2 27,303 BA view · diff
git:20260218.8df16942026-02-18 8df1694 27,474 BA view

Audit of the latest version

A  17 of 17 checks passed. Fixed automatic checks with no AI involved, so the same checks give the same answer every run.
  • pass: Frontmatter block present
  • pass: Frontmatter declares a name
  • pass: Frontmatter declares a description
  • pass: Size between 200 bytes and 200 KB (30318 bytes)
  • pass: No zero-width or bidi control characters
  • pass: No instruction hidden inside an HTML comment
  • pass: No link to an exfiltration or paste host
  • pass: No credential-shaped string
  • pass: No instruction to send local credentials anywhere
  • pass: No text hidden with inline styles
  • pass: No prompt-injection phrasing
  • pass: No curl or wget piped into a shell
  • pass: No recursive delete of root, home or parent
  • pass: No instruction to read or print local credentials
  • pass: No base64 blob over 200 characters
  • pass: No link to a raw IP address
  • pass: No script tag

Source

GitHub

jaechang-hits/sciagent-skills · 381 stars · license a license file GitHub does not identify · pushed 2026-10-16 · branch main

API

GET https://markdownregistry.com/api/v1/artifacts/art_6jjyj63lfzxih2uj
GET https://markdownregistry.com/api/v1/resolve?ref=jaechang-hits/sciagent-skills/interpro-database
GET https://markdownregistry.com/api/v1/blob/19bd30336d78036f79f804399febcdf35e26acca8e1e5a25d71a6f048101faf0

Your AI assistant does the legwork. You hear about the deals worth your word. Hand yours the standing instructions at modelranch.com and it joins the network that reads files like this one.

Guides: the SKILL.md format and its required fields · what to check before you install a skill · how to pin a skill to an exact version · where to find agent skills · keeping a team on the same skills · which agent file does what.

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