Home / ammawla / encode-toolkit · plugin/skills/ucsc-browser/SKILL.md · GitHub

ucsc-browser skillA

ucsc-browser is agent-read markdown (skill) from ammawla/encode-toolkit: Query the UCSC Genome Browser REST API to retrieve regulatory tracks, DNA sequences, cCRE annotations, TF binding clusters, and track schemas for any genomic region. Use when the user wants to look up what regulatory elements exist at a genomic locus, retrieve DNA sequence under peaks, query ENCODE cCREs or TF rPeak clusters from UCSC, check what tracks are available for a genome assembly, get chromatin accessibility across cell types, or cross-reference ENCODE data with UCSC-hosted annotations..

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What the file says

# Query the UCSC Genome Browser REST API

## When to Use

- User wants to query the UCSC Genome Browser REST API for tracks, sequences, or cCRE annotations
- User asks about "UCSC", "genome browser", "cCREs", "track hub", or "sequence retrieval"
- User needs to retrieve DNA sequences for peak regions or regulatory elements
- User wants to intersect ENCODE peaks with UCSC-hosted annotations (cCREs, conservation, repeat masker)
- Example queries: "get cCRE annotations for my region", "fetch DNA sequence under my peaks", "query UCSC for conservation scores at my enhancers"

Retrieve regulatory annotations, DNA sequences, TF binding data, and ENCODE-hosted tracks from the UCSC Genome Browser programmatic interface.

## Scientific Rationale

**The question**: "What regulatory annotations exist at this genomic locus, and what is the underlying sequence?"
…

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How to install

Latest version
mdr add ammawla/encode-toolkit/ucsc-browser@git:20260920.6050003
Exact content
mdr add ammawla/encode-toolkit/ucsc-browser@sha256:8096b5cc4cd754ee

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Versions

versioncommittedcommitsizeaudit
git:20260920.6050003 latest2026-09-20 6050003 17,018 BA view · diff
git:20260920.ce7840d2026-09-20 ce7840d 16,597 BA view · diff
git:20260312.be327062026-03-12 be32706 16,586 BA view

Audit of the latest version

A  17 of 17 checks passed. Deterministic, no model, same answer every run.
  • pass: Frontmatter block present
  • pass: Frontmatter declares a name
  • pass: Frontmatter declares a description
  • pass: Size between 200 bytes and 200 KB (17018 bytes)
  • pass: No zero-width or bidi control characters
  • pass: No instruction hidden inside an HTML comment
  • pass: No link to an exfiltration or paste host
  • pass: No credential-shaped string
  • pass: No instruction to send local credentials anywhere
  • pass: No text hidden with inline styles
  • pass: No prompt-injection phrasing
  • pass: No curl or wget piped into a shell
  • pass: No recursive delete of root, home or parent
  • pass: No instruction to read or print local credentials
  • pass: No base64 blob over 200 characters
  • pass: No link to a raw IP address
  • pass: No script tag

Source

GitHub

ammawla/encode-toolkit · 20 stars · license AGPL-3.0 · pushed 2026-09-21 · branch main

API

GET https://markdownregistry.com/api/v1/artifacts/art_ajyucus2cdkrakzq
GET https://markdownregistry.com/api/v1/resolve?ref=ammawla/encode-toolkit/ucsc-browser
GET https://markdownregistry.com/api/v1/blob/8096b5cc4cd754eeb61ba4963f6eff84e9ad4bc62739d3a165a5259549da7a74

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