indication-dossier SKILL.md skillA
indication-dossier from xuzhougeng/wisp-science is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.
mdr add xuzhougeng/wisp-science/indication-dossier@git:20260816.42573ebPins git:20260816.42573eb in mdr.lock. Pin the fingerprint instead.
- Audit grade
- A, 17 of 17 checks passed
- Kind
- SKILL.md skill
- Repository
- xuzhougeng/wisp-science
- Path
skills/indication-dossier/SKILL.md- Versions recorded
- 3
- Latest version
- git:20260816.42573eb, committed Aug 16, 2026
- First version recorded
- Jul 1, 2026
- Size
- 4,115 bytes
- Repository stars
- 1,068
- License
- AGPL-3.0
Build a sourced research dossier for one therapeutic indication — patient population, epidemiology, disease biology, standard of care, regulatory path, and landmark trials. Use when the user asks for an indication overview, disease landscape, or trial-design background.
Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.
What the file says
# Indication dossier
Five research phases, each writing one waypoint JSON under
`<workdir>/waypoints/`, ending in a cited Markdown report. Waypoints make the
run resumable: a later invocation reads which files exist and continues from
the first missing one. The only pause for user input is after Phase 1.
## The framing rule
Treat the indication as a *patient population*, not a disease entry. Every
section answers a population question — who are these patients, how are they
identified and managed, which trials would help them — rather than a textbook
question about the condition. Nesting is population nesting: everyone in the
child indication is in the parent.
Some inputs are not billable diagnoses at all: a biological state
("immunosenescence"), a non-accepted indication ("ageing"), an iatrogenic
population ("GLP-1 induced sarcopenia"). Detect and label this early — it
changes the epidemiology evidence base, the regulatory path, and what a
"complete" dossier even looks like.
## Inputs
| Input | Required | Meaning |
|---|---|---|
| `indication` | yes | e.g. "sarcopenia", "idiopathic pulmonary fibrosis" |
| `additional_context` | no | focus areas, parent indication, framing |
…Read the whole file at its exact version.
How to install
mdr add xuzhougeng/wisp-science/indication-dossier@sha256:46c0d213d29c45b0The line at the top of this page pins the label git:20260816.42573eb, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.
[](https://markdownregistry.com/a/art_d4y5efxgh4c35hyj)
5 badge image fetches in 30 days. What the badge shows.
Versions
The registry has recorded 3 versions of this file, between Jul 1, 2026 and Aug 16, 2026, about one every 23 days.
| version | committed | commit | size | audit | |
|---|---|---|---|---|---|
| git:20260816.42573eb latest | 2026-08-16 | 42573eb | 4,115 B | A | view · diff |
| git:20260721.77e7d29 | 2026-07-21 | 77e7d29 | 5,839 B | A | view · diff |
| git:20260701.17c5369 | 2026-07-01 | 17c5369 | 5,875 B | A | view |
Audit of the latest version
- pass: Frontmatter block present
- pass: Frontmatter declares a name
- pass: Frontmatter declares a description
- pass: Size between 200 bytes and 200 KB (4115 bytes)
- pass: No zero-width or bidi control characters
- pass: No instruction hidden inside an HTML comment
- pass: No link to an exfiltration or paste host
- pass: No credential-shaped string
- pass: No instruction to send local credentials anywhere
- pass: No text hidden with inline styles
- pass: No prompt-injection phrasing
- pass: No curl or wget piped into a shell
- pass: No recursive delete of root, home or parent
- pass: No instruction to read or print local credentials
- pass: No base64 blob over 200 characters
- pass: No link to a raw IP address
- pass: No script tag
Source
xuzhougeng/wisp-science · 1,068 stars · license AGPL-3.0 · pushed 2026-11-09 · branch main
API
GET https://markdownregistry.com/api/v1/artifacts/art_d4y5efxgh4c35hyj GET https://markdownregistry.com/api/v1/resolve?ref=xuzhougeng/wisp-science/indication-dossier GET https://markdownregistry.com/api/v1/blob/46c0d213d29c45b0e4c9d0bf7c6bdcc0ba99a8099c3c046a2a53732c9d27ef1d
Your AI assistant does the legwork. You hear about the deals worth your word. Hand yours the standing instructions at modelranch.com and it joins the network that reads files like this one.
Guides: the SKILL.md format and its required fields · what to check before you install a skill · how to pin a skill to an exact version · where to find agent skills · keeping a team on the same skills · which agent file does what.
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