indication-dossier SKILL.md skillA
indication-dossier from pengqianhan/ai-human-research-os is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.
mdr add pengqianhan/ai-human-research-os/indication-dossier@git:20260715.38d79bePins git:20260715.38d79be in mdr.lock. Pin the fingerprint instead.
- Audit grade
- A, 17 of 17 checks passed
- Kind
- SKILL.md skill
- Repository
- pengqianhan/ai-human-research-os
- Path
research-skills-hub/claude-science-skills/skills/indication-dossier/SKILL.md- Versions recorded
- 1
- Latest version
- git:20260715.38d79be, committed Jul 15, 2026
- Size
- 5,875 bytes
- Repository stars
- 3
- License
- MIT
Generate a therapeutic indication dossier. Covers the patient population, epidemiology, disease biology, standard of care, regulatory precedent, and landmark clinical trials.
Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.
What the file says
# Indication Dossier
Produces a structured research dossier on a single indication, framed as a
patient population: who they are, what's wrong, how they're treated today,
and how clinical trials can be designed to help them. Runs as five phases
that write resumable waypoint files; after a brief identity check at the end
of Phase 1, the remaining phases run straight through.
## Framing
**Think of an indication as a patient population.** Frame everything
from the patient perspective: "Who are these patients?" not "What is this
disease?"; "How are these patients identified and managed?" not "What causes
this condition?"; population nesting: "all patients in {child} are patients
in {parent}".
Some indications don't map to ICD codes or standard disease definitions:
"immunosenescence" is a biological state, not a billable diagnosis; "ageing"
is not an FDA-accepted indication; "GLP-1 induced sarcopenia" is an
iatrogenic population. Note these distinctions explicitly. They matter for
regulatory path and trial design.
## Inputs
- **`indication`** (required) — indication name (e.g., "sarcopenia",
"idiopathic pulmonary fibrosis").
…Read the whole file at its exact version.
How to install
mdr add pengqianhan/ai-human-research-os/indication-dossier@sha256:dfad982f985e7db5The line at the top of this page pins the label git:20260715.38d79be, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.
[](https://markdownregistry.com/a/art_k5smj3n7kxwbp4kh)
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Versions
The registry has recorded 1 version of this file, committed on Jul 15, 2026.
Audit of the latest version
- pass: Frontmatter block present
- pass: Frontmatter declares a name
- pass: Frontmatter declares a description
- pass: Size between 200 bytes and 200 KB (5875 bytes)
- pass: No zero-width or bidi control characters
- pass: No instruction hidden inside an HTML comment
- pass: No link to an exfiltration or paste host
- pass: No credential-shaped string
- pass: No instruction to send local credentials anywhere
- pass: No text hidden with inline styles
- pass: No prompt-injection phrasing
- pass: No curl or wget piped into a shell
- pass: No recursive delete of root, home or parent
- pass: No instruction to read or print local credentials
- pass: No base64 blob over 200 characters
- pass: No link to a raw IP address
- pass: No script tag
Source
pengqianhan/ai-human-research-os · 3 stars · license MIT · pushed 2026-10-19 · branch main
API
GET https://markdownregistry.com/api/v1/artifacts/art_k5smj3n7kxwbp4kh GET https://markdownregistry.com/api/v1/resolve?ref=pengqianhan/ai-human-research-os/indication-dossier GET https://markdownregistry.com/api/v1/blob/dfad982f985e7db5a406420b108713c0b8ce39903e304a3f968d11271c9e64ec
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Guides: the SKILL.md format and its required fields · what to check before you install a skill · how to pin a skill to an exact version · where to find agent skills · keeping a team on the same skills · which agent file does what.
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