hypogenic-hypothesis-generation SKILL.md skillA

hypogenic-hypothesis-generation from jaechang-hits/sciagent-skills is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.

Install it, pinned
mdr add jaechang-hits/sciagent-skills/hypogenic-hypothesis-generation@git:20260428.81ea2d2

Pins git:20260428.81ea2d2 in mdr.lock. Pin the fingerprint instead.

Audit grade
A, 17 of 17 checks passed
Kind
SKILL.md skill
Repository
jaechang-hits/sciagent-skills
Path
skills/scientific-computing/hypogenic-hypothesis-generation/SKILL.md
Versions recorded
2
Latest version
git:20260428.81ea2d2, committed Apr 28, 2026
First version recorded
Feb 18, 2026
Size
15,670 bytes
Repository stars
381
License
a license file GitHub does not identify

LLM-driven hypothesis generation/testing on tabular data. Three methods: HypoGeniC (data-driven), HypoRefine (literature+data), Union. Iterative refinement, Redis caching, multi-hypothesis inference. Manual: hypothesis-generation; ideation: scientific-brainstorming.

Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.

What the file says

# HypoGeniC Hypothesis Generation

## Overview

HypoGeniC automates scientific hypothesis generation and testing using LLMs on tabular datasets. Given labeled data (e.g., deception detection, AI-content identification), it generates testable hypotheses, iteratively refines them against validation performance, and runs inference to classify new samples. It supports three approaches: purely data-driven (HypoGeniC), literature-integrated (HypoRefine), and mechanistic union of both.

## When to Use

- Generating testable hypotheses from labeled observational datasets without prior theory
- Systematically testing multiple competing hypotheses on empirical data
- Combining insights from research papers with data-driven pattern discovery
- Accelerating hypothesis ideation in domains like deception detection, content analysis, mental health indicators
- Benchmarking LLM-based hypothesis generation methods against few-shot baselines
- For manual hypothesis formulation frameworks, use **hypothesis-generation** knowhow
- For general-purpose ML classification without hypothesis interpretability, use **scikit-learn-machine-learning**

## Prerequisites

- **Python packages**: `hypogenic`
…

Read the whole file at its exact version.

How to install

The exact contents, by fingerprint
mdr add jaechang-hits/sciagent-skills/hypogenic-hypothesis-generation@sha256:be1abe14f2426f24

The line at the top of this page pins the label git:20260428.81ea2d2, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.

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Versions

The registry has recorded 2 versions of this file, between Feb 18, 2026 and Apr 28, 2026, about one every 69 days.

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git:20260428.81ea2d2 latest2026-04-28 81ea2d2 15,670 BA view · diff
git:20260218.8df16942026-02-18 8df1694 15,766 BA view

Audit of the latest version

A  17 of 17 checks passed. Fixed automatic checks with no AI involved, so the same checks give the same answer every run.
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  • pass: Frontmatter declares a name
  • pass: Frontmatter declares a description
  • pass: Size between 200 bytes and 200 KB (15670 bytes)
  • pass: No zero-width or bidi control characters
  • pass: No instruction hidden inside an HTML comment
  • pass: No link to an exfiltration or paste host
  • pass: No credential-shaped string
  • pass: No instruction to send local credentials anywhere
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Source

GitHub

jaechang-hits/sciagent-skills · 381 stars · license a license file GitHub does not identify · pushed 2026-10-16 · branch main

API

GET https://markdownregistry.com/api/v1/artifacts/art_dcqyhdtmj4e73kh6
GET https://markdownregistry.com/api/v1/resolve?ref=jaechang-hits/sciagent-skills/hypogenic-hypothesis-generation
GET https://markdownregistry.com/api/v1/blob/be1abe14f2426f240e678b989f8d74ac894a5226394cc494231ab5ddce7ac4a8

Your AI assistant does the legwork. You hear about the deals worth your word. Hand yours the standing instructions at modelranch.com and it joins the network that reads files like this one.

Guides: the SKILL.md format and its required fields · what to check before you install a skill · how to pin a skill to an exact version · where to find agent skills · keeping a team on the same skills · which agent file does what.

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