dbsnp-database SKILL.md skillA
dbsnp-database from jaechang-hits/sciagent-skills is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.
mdr add jaechang-hits/sciagent-skills/dbsnp-database@git:20260528.3e3f998Pins git:20260528.3e3f998 in mdr.lock. Pin the fingerprint instead.
- Audit grade
- A, 17 of 17 checks passed
- Kind
- SKILL.md skill
- Repository
- jaechang-hits/sciagent-skills
- Path
skills/genomics-bioinformatics/databases/dbsnp-database/SKILL.md- Versions recorded
- 1
- Latest version
- git:20260528.3e3f998, committed May 28, 2026
- Size
- 29,143 bytes
- Repository stars
- 381
- License
- a license file GitHub does not identify
Query NCBI dbSNP for SNP records by rsID, gene, or region via E-utilities and Variation Services REST API. Retrieve alleles, MAF, variant class (SNV/indel/MNV), clinical links, cross-DB IDs (ClinVar, dbVar, 1000G). Free; 3 req/sec (10 with key). For clinical pathogenicity use clinvar-database; for population frequencies use gnomad-database.
Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.
What the file says
# dbSNP Database ## Overview NCBI dbSNP is the primary public repository for short human genetic variants, cataloguing over 1 billion SNPs, indels, and MNVs with allele frequencies, functional annotations, and cross-references to ClinVar, gnomAD, and 1000 Genomes. Variants are identified by stable rsIDs (reference SNP cluster IDs). Access is free via two APIs: the legacy NCBI E-utilities and the newer NCBI Variation Services REST API, which returns structured JSON. ## When to Use - Looking up allele frequencies and variant class for a known rsID - Searching all dbSNP variants in a gene or chromosomal region by name or coordinates - Resolving rsIDs to genomic coordinates (GRCh38/GRCh37) and HGVS notation - Checking whether a variant of interest has clinical significance links to ClinVar entries - Batch-fetching hundreds of rsIDs efficiently using epost+efetch history server - Cross-referencing a list of variant positions to dbSNP rsIDs for downstream annotation - For clinical pathogenicity classifications use `clinvar-database`; dbSNP provides IDs and frequency but not curated clinical significance …
Read the whole file at its exact version.
How to install
mdr add jaechang-hits/sciagent-skills/dbsnp-database@sha256:1b13f61a552403d6The line at the top of this page pins the label git:20260528.3e3f998, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.
[](https://markdownregistry.com/a/art_igthsalw4g4fklis)
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Versions
The registry has recorded 1 version of this file, committed on May 28, 2026.
Audit of the latest version
- pass: Frontmatter block present
- pass: Frontmatter declares a name
- pass: Frontmatter declares a description
- pass: Size between 200 bytes and 200 KB (29143 bytes)
- pass: No zero-width or bidi control characters
- pass: No instruction hidden inside an HTML comment
- pass: No link to an exfiltration or paste host
- pass: No credential-shaped string
- pass: No instruction to send local credentials anywhere
- pass: No text hidden with inline styles
- pass: No prompt-injection phrasing
- pass: No curl or wget piped into a shell
- pass: No recursive delete of root, home or parent
- pass: No instruction to read or print local credentials
- pass: No base64 blob over 200 characters
- pass: No link to a raw IP address
- pass: No script tag
Source
jaechang-hits/sciagent-skills · 381 stars · license a license file GitHub does not identify · pushed 2026-10-16 · branch main
API
GET https://markdownregistry.com/api/v1/artifacts/art_igthsalw4g4fklis GET https://markdownregistry.com/api/v1/resolve?ref=jaechang-hits/sciagent-skills/dbsnp-database GET https://markdownregistry.com/api/v1/blob/1b13f61a552403d69d5569b79006b624acff8c6a030f7e66cf6ddcf7f83dff86
Your AI assistant does the legwork. You hear about the deals worth your word. Hand yours the standing instructions at modelranch.com and it joins the network that reads files like this one.
Guides: the SKILL.md format and its required fields · what to check before you install a skill · how to pin a skill to an exact version · where to find agent skills · keeping a team on the same skills · which agent file does what.