sar-analysis SKILL.md skillA
sar-analysis from jaechang-hits/sciagent-skills is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.
mdr add jaechang-hits/sciagent-skills/sar-analysis@git:20260502.5e39ba9Pins git:20260502.5e39ba9 in mdr.lock. Pin the fingerprint instead.
- Audit grade
- A, 17 of 17 checks passed
- Kind
- SKILL.md skill
- Repository
- jaechang-hits/sciagent-skills
- Path
skills/structural-biology-drug-discovery/sar-analysis/SKILL.md- Versions recorded
- 4
- Latest version
- git:20260502.5e39ba9, committed May 2, 2026
- First version recorded
- Mar 30, 2026
- Size
- 23,276 bytes
- Repository stars
- 381
- License
- a license file GitHub does not identify
Structure-activity relationship (SAR) analysis guide for drug discovery including molecular descriptor analysis, scaffold analysis, and activity cliff detection.
Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.
What the file says
# SAR Analysis --- ## Metadata **Short Description**: Comprehensive guide for performing Structure-Activity Relationship (SAR) analysis using RDKit. **Authors**: Ohagent Team **Version**: 1.0 **Last Updated**: December 2025 **License**: CC BY 4.0 **Commercial Use**: ✅ Allowed --- ## Overview Structure-Activity Relationship (SAR) analysis is a core medicinal-chemistry workflow that relates systematic structural variations of a chemical series to changes in biological activity. The goal is to (1) identify a common scaffold (Maximum Common Substructure, MCS) shared by a series of analogues, (2) decompose each molecule into the scaffold plus its R-group substituents, (3) align all molecules so substituents at equivalent positions are visually comparable, and (4) connect substituent variation to potency to derive testable design hypotheses. …
Read the whole file at its exact version.
How to install
mdr add jaechang-hits/sciagent-skills/sar-analysis@sha256:c7cbffdf55d79ad4The line at the top of this page pins the label git:20260502.5e39ba9, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.
[](https://markdownregistry.com/a/art_kbpfybt6avnbi5wj)
1 badge image fetches in 30 days. What the badge shows.
Versions
The registry has recorded 4 versions of this file, between Mar 30, 2026 and May 2, 2026, about one every 11 days.
| version | committed | commit | size | audit | |
|---|---|---|---|---|---|
| git:20260502.5e39ba9 latest | 2026-05-02 | 5e39ba9 | 23,276 B | A | view · diff |
| git:20260428.81ea2d2 | 2026-04-28 | 81ea2d2 | 20,715 B | A | view · diff |
| git:20260331.51dcb8c | 2026-03-31 | 51dcb8c | 20,847 B | A | view · diff |
| v1.0 | 2026-03-30 | b392569 | 11,689 B | A | view |
Audit of the latest version
- pass: Frontmatter block present
- pass: Frontmatter declares a name
- pass: Frontmatter declares a description
- pass: Size between 200 bytes and 200 KB (23276 bytes)
- pass: No zero-width or bidi control characters
- pass: No instruction hidden inside an HTML comment
- pass: No link to an exfiltration or paste host
- pass: No credential-shaped string
- pass: No instruction to send local credentials anywhere
- pass: No text hidden with inline styles
- pass: No prompt-injection phrasing
- pass: No curl or wget piped into a shell
- pass: No recursive delete of root, home or parent
- pass: No instruction to read or print local credentials
- pass: No base64 blob over 200 characters
- pass: No link to a raw IP address
- pass: No script tag
Source
jaechang-hits/sciagent-skills · 381 stars · license a license file GitHub does not identify · pushed 2026-10-16 · branch main
API
GET https://markdownregistry.com/api/v1/artifacts/art_kbpfybt6avnbi5wj GET https://markdownregistry.com/api/v1/resolve?ref=jaechang-hits/sciagent-skills/sar-analysis GET https://markdownregistry.com/api/v1/blob/c7cbffdf55d79ad4aa3e1e9454b6a1ba16c702866c6f742ce61ca190f36c5d21
Your AI assistant does the legwork. You hear about the deals worth your word. Hand yours the standing instructions at modelranch.com and it joins the network that reads files like this one.
Guides: the SKILL.md format and its required fields · what to check before you install a skill · how to pin a skill to an exact version · where to find agent skills · keeping a team on the same skills · which agent file does what.