aipoch/open-science · resources/skills/proteinmpnn/SKILL.md

proteinmpnn skillA

proteinmpnn is agent-read markdown (skill) from aipoch/open-science: Inverse-fold a protein backbone (PDB structure) into amino-acid sequence with ProteinMPNN (Dauparas et al. 2022, github.com/dauparas/ProteinMPNN). Reach for this skill to run sequence design on RFdiffusion backbones, to redesign one chain of a PDB while holding interface residues fixed, or to generate a temperature-swept set of sequences for downstream folding..

Indexed from public GitHub and served as immutable, content-addressed versions. Install it pinned to an exact SHA-256 with the mdr CLI, and every file is verified against the hash recorded here before it reaches your agent. The deterministic audit below grades the latest version, and the same file always earns the same grade.

How to install

Latest version
mdr add aipoch/open-science/proteinmpnn@git:20260814.c9a70d8
Exact content
mdr add aipoch/open-science/proteinmpnn@sha256:fb284aced53d394b

Pin to a label to follow the author's releases, or to a sha256 to freeze the exact bytes forever. Either way the resolved hash is written to mdr.lock, and mdr install reproduces it on any machine.

Badge

mdr badge

[![mdr](https://markdownregistry.com/badge/art_qaqzdxo3flu5duup.svg)](https://markdownregistry.com/a/art_qaqzdxo3flu5duup)

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Versions

versioncommittedcommitsizeaudit
git:20260814.c9a70d8 latest2026-08-14 c9a70d8 5,258 BA view · diff
git:20260714.a2a32822026-07-14 a2a3282 4,587 BA view

Audit of the latest version

A  17 of 17 checks passed. Deterministic, no model, same answer every run.

Source

GitHub

aipoch/open-science · 3,699 stars · license Apache-2.0 · pushed 2026-09-06 · branch main

API

GET https://markdownregistry.com/api/v1/artifacts/art_qaqzdxo3flu5duup
GET https://markdownregistry.com/api/v1/resolve?ref=aipoch/open-science/proteinmpnn
GET https://markdownregistry.com/api/v1/blob/fb284aced53d394b82411b022ab00ff1da07be2fd16da4d4d08d28d6e74540ba