proteinmpnn is agent-read markdown (skill) from aipoch/open-science: Inverse-fold a protein backbone (PDB structure) into amino-acid sequence with ProteinMPNN (Dauparas et al. 2022, github.com/dauparas/ProteinMPNN). Reach for this skill to run sequence design on RFdiffusion backbones, to redesign one chain of a PDB while holding interface residues fixed, or to generate a temperature-swept set of sequences for downstream folding..
Indexed from public GitHub and served as immutable, content-addressed versions. Install it pinned to an exact SHA-256 with the mdr CLI, and every file is verified against the hash recorded here before it reaches your agent. The deterministic audit below grades the latest version, and the same file always earns the same grade.
mdr add aipoch/open-science/proteinmpnn@git:20260814.c9a70d8mdr add aipoch/open-science/proteinmpnn@sha256:fb284aced53d394bPin to a label to follow the author's releases, or to a sha256 to freeze the exact bytes forever. Either way the resolved hash is written to mdr.lock, and mdr install reproduces it on any machine.
[](https://markdownregistry.com/a/art_qaqzdxo3flu5duup)
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| version | committed | commit | size | audit | |
|---|---|---|---|---|---|
| git:20260814.c9a70d8 latest | 2026-08-14 | c9a70d8 | 5,258 B | A | view · diff |
| git:20260714.a2a3282 | 2026-07-14 | a2a3282 | 4,587 B | A | view |
aipoch/open-science · 3,699 stars · license Apache-2.0 · pushed 2026-09-06 · branch main
GET https://markdownregistry.com/api/v1/artifacts/art_qaqzdxo3flu5duup GET https://markdownregistry.com/api/v1/resolve?ref=aipoch/open-science/proteinmpnn GET https://markdownregistry.com/api/v1/blob/fb284aced53d394b82411b022ab00ff1da07be2fd16da4d4d08d28d6e74540ba