calc-sample-size SKILL.md skillA
calc-sample-size from aperivue/medsci-skills is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.
mdr add aperivue/medsci-skills/calc-sample-size@git:20260930.c8ed96cPins git:20260930.c8ed96c in mdr.lock. Pin the fingerprint instead.
- Audit grade
- A, 17 of 17 checks passed
- Kind
- SKILL.md skill
- Repository
- aperivue/medsci-skills
- Path
skills/calc-sample-size/SKILL.md- Versions recorded
- 9
- Latest version
- git:20260930.c8ed96c, committed Sep 30, 2026
- First version recorded
- Jul 25, 2026
- Size
- 11,713 bytes
- Repository stars
- 346
- License
- MIT
Use when planning how many patients or cases a study needs before data collection (power analysis, IRB justification). Walks a decision tree to the right test and returns reproducible R/Python code and IRB-ready justification text. Analyzing collected data is /analyze-stats.
Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.
What the file says
# Calc-Sample-Size Skill ## Decision Tree Walk the user through this tree one question at a time; do not assume answers. Reader studies, segmentation and model-comparison designs sit outside the tree: see Tests 14–17. ``` What is your primary outcome? | +-- Binary (yes/no, positive/negative) | | | +-- Paired data (same subjects, two methods)? | | +-- YES --> [5] McNemar test | | +-- NO --> How many groups? | | +-- 2 groups, superiority --> [4] Two-proportion comparison (chi-square) | | +-- 2 groups, non-inferiority --> [10] Non-inferiority / equivalence | | +-- Multivariable model --> single-predictor hypothesis test? --> [9] Logistic regression | | --> clinical prediction / AI model for use? | | +-- developing the model --> [12] Prediction-model development (Riley) | | +-- externally validating --> [13] External-validation (Riley) | | +-- Continuous (measurement, score) | | | +-- How many groups? | +-- 2 groups --> [6] Independent t-test | +-- 3+ groups --> [8] One-way ANOVA | …
Read the whole file at its exact version.
How to install
mdr add aperivue/medsci-skills/calc-sample-size@sha256:ee07845a609e1132The line at the top of this page pins the label git:20260930.c8ed96c, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.
[](https://markdownregistry.com/a/art_t5xp7q5rkbbf6urd)
5 badge image fetches in 30 days. What the badge shows.
Versions
The registry has recorded 9 versions of this file, between Jul 25, 2026 and Sep 30, 2026, about one every 8 days.
| version | committed | commit | size | audit | |
|---|---|---|---|---|---|
| git:20260930.c8ed96c latest | 2026-09-30 | c8ed96c | 11,713 B | A | view · diff |
| git:20260930.30387c2 | 2026-09-30 | 30387c2 | 11,234 B | A | view · diff |
| git:20260930.006deab | 2026-09-30 | 006deab | 11,335 B | A | view · diff |
| git:20260930.69d672e | 2026-09-30 | 69d672e | 11,120 B | A | view · diff |
| git:20260725.67fd47f | 2026-07-25 | 67fd47f | 33,435 B | A | view · diff |
| git:20260725.c63ec3d | 2026-07-25 | c63ec3d | 30,637 B | A | view · diff |
| git:20260725.13ac006 | 2026-07-25 | 13ac006 | 30,513 B | A | view · diff |
| git:20260725.3afcebb | 2026-07-25 | 3afcebb | 27,695 B | A | view · diff |
| git:20260725.626d95a | 2026-07-25 | 626d95a | 25,878 B | A | view |
Audit of the latest version
- pass: Frontmatter block present
- pass: Frontmatter declares a name
- pass: Frontmatter declares a description
- pass: Size between 200 bytes and 200 KB (11713 bytes)
- pass: No zero-width or bidi control characters
- pass: No instruction hidden inside an HTML comment
- pass: No link to an exfiltration or paste host
- pass: No credential-shaped string
- pass: No instruction to send local credentials anywhere
- pass: No text hidden with inline styles
- pass: No prompt-injection phrasing
- pass: No curl or wget piped into a shell
- pass: No recursive delete of root, home or parent
- pass: No instruction to read or print local credentials
- pass: No base64 blob over 200 characters
- pass: No link to a raw IP address
- pass: No script tag
Source
aperivue/medsci-skills · 346 stars · license MIT · pushed 2026-10-19 · branch main
API
GET https://markdownregistry.com/api/v1/artifacts/art_t5xp7q5rkbbf6urd GET https://markdownregistry.com/api/v1/resolve?ref=aperivue/medsci-skills/calc-sample-size GET https://markdownregistry.com/api/v1/blob/ee07845a609e1132a8e093b1fabd708561bedc634fccd82bfa3362e7eea93b2f
Your AI assistant does the legwork. You hear about the deals worth your word. Hand yours the standing instructions at modelranch.com and it joins the network that reads files like this one.
Guides: the SKILL.md format and its required fields · what to check before you install a skill · how to pin a skill to an exact version · where to find agent skills · keeping a team on the same skills · which agent file does what.