evo2 SKILL.md skillA
evo2 from pengqianhan/ai-human-research-os is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.
mdr add pengqianhan/ai-human-research-os/evo2@git:20260715.38d79bePins git:20260715.38d79be in mdr.lock. Pin the fingerprint instead.
- Audit grade
- A, 17 of 17 checks passed
- Kind
- SKILL.md skill
- Repository
- pengqianhan/ai-human-research-os
- Path
research-skills-hub/claude-science-skills/skills/evo2/SKILL.md- Versions recorded
- 1
- Latest version
- git:20260715.38d79be, committed Jul 15, 2026
- Size
- 5,418 bytes
- Repository stars
- 3
- License
- MIT
Score, embed, and generate DNA sequences with Evo 2, a long-context genomic foundation model. Use this skill when: (1) Computing per-nucleotide or per-sequence likelihoods for variant effect scoring, (2) Embedding genomic windows for downstream classification, (3) Generating DNA conditioned on a prefix, (4) Scoring regulatory or coding regions across species.
Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.
What the file says
# Evo 2 — DNA Language Model
## Prerequisites
| Requirement | Minimum | Recommended |
| ----------- | ------- | ---------------- |
| Python | 3.11 | 3.12 (<3.13) |
| CUDA | 12.1+ | 12.4+ |
| GPU VRAM | 24 GB (7B bf16) | 80 GB (40B) |
| RAM | 32 GB | 128 GB |
## How to run
### Installation
```bash
pip install evo2
# Weights pulled from Hugging Face on first model load.
```
### Loading and scoring
```python
from evo2 import Evo2
model = Evo2("evo2_7b") # or "evo2_40b" — see model table
seqs = ["ATCG" * 50, "GGGCTTAA" * 25]
ll = model.score_sequences(seqs) # → list[float], mean per-token log-likelihood
print(ll)
```
### Generation
```python
out = model.generate(
prompt_seqs=["ATGAAAGCT"],
n_tokens=256,
temperature=0.7,
)
print(out.sequences[0])
```
## Models
| Name | Params | Context | VRAM (bf16) | Notes |
| ----------- | ------ | ------- | ----------- | ---------------------------------- |
| `evo2_7b` | 7 B | 1 M nt | ~22 GB | Default; fits on a single 24 GB+ GPU |
…Read the whole file at its exact version.
How to install
mdr add pengqianhan/ai-human-research-os/evo2@sha256:fe826880691971edThe line at the top of this page pins the label git:20260715.38d79be, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.
[](https://markdownregistry.com/a/art_u2kuow3sdcfsqusl)
3 badge image fetches in 30 days. What the badge shows.
Versions
The registry has recorded 1 version of this file, committed on Jul 15, 2026.
Audit of the latest version
- pass: Frontmatter block present
- pass: Frontmatter declares a name
- pass: Frontmatter declares a description
- pass: Size between 200 bytes and 200 KB (5418 bytes)
- pass: No zero-width or bidi control characters
- pass: No instruction hidden inside an HTML comment
- pass: No link to an exfiltration or paste host
- pass: No credential-shaped string
- pass: No instruction to send local credentials anywhere
- pass: No text hidden with inline styles
- pass: No prompt-injection phrasing
- pass: No curl or wget piped into a shell
- pass: No recursive delete of root, home or parent
- pass: No instruction to read or print local credentials
- pass: No base64 blob over 200 characters
- pass: No link to a raw IP address
- pass: No script tag
Source
pengqianhan/ai-human-research-os · 3 stars · license MIT · pushed 2026-10-19 · branch main
API
GET https://markdownregistry.com/api/v1/artifacts/art_u2kuow3sdcfsqusl GET https://markdownregistry.com/api/v1/resolve?ref=pengqianhan/ai-human-research-os/evo2 GET https://markdownregistry.com/api/v1/blob/fe826880691971ed32e472b63e3d99be104ce2afc0e78ce50a332c26642e9fe1
Your AI assistant does the legwork. You hear about the deals worth your word. Hand yours the standing instructions at modelranch.com and it joins the network that reads files like this one.
Guides: the SKILL.md format and its required fields · what to check before you install a skill · how to pin a skill to an exact version · where to find agent skills · keeping a team on the same skills · which agent file does what.
More from pengqianhan/ai-human-research-os
Every file in pengqianhan/ai-human-research-os