aipoch/open-science · resources/skills/evo2/SKILL.md

evo2 skillA

evo2 is agent-read markdown (skill) from aipoch/open-science: Score, embed, and generate DNA sequences with Evo 2, a long-context genomic foundation model. Use this skill when: (1) Computing per-nucleotide or per-sequence likelihoods for variant effect scoring, (2) Embedding genomic windows for downstream classification, (3) Generating DNA conditioned on a prefix, (4) Scoring regulatory or coding regions across species..

Indexed from public GitHub and served as immutable, content-addressed versions. Install it pinned to an exact SHA-256 with the mdr CLI, and every file is verified against the hash recorded here before it reaches your agent. The deterministic audit below grades the latest version, and the same file always earns the same grade.

How to install

Latest version
mdr add aipoch/open-science/evo2@git:20260811.e7618cb
Exact content
mdr add aipoch/open-science/evo2@sha256:95f2a4439715857f

Pin to a label to follow the author's releases, or to a sha256 to freeze the exact bytes forever. Either way the resolved hash is written to mdr.lock, and mdr install reproduces it on any machine.

Badge

mdr badge

[![mdr](https://markdownregistry.com/badge/art_nhkvvzq6qjq56i4u.svg)](https://markdownregistry.com/a/art_nhkvvzq6qjq56i4u)

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Versions

versioncommittedcommitsizeaudit
git:20260811.e7618cb latest2026-08-11 e7618cb 5,460 BA view · diff
git:20260714.a2a32822026-07-14 a2a3282 5,418 BA view

Audit of the latest version

A  17 of 17 checks passed. Deterministic, no model, same answer every run.

Source

GitHub

aipoch/open-science · 3,699 stars · license Apache-2.0 · pushed 2026-09-06 · branch main

API

GET https://markdownregistry.com/api/v1/artifacts/art_nhkvvzq6qjq56i4u
GET https://markdownregistry.com/api/v1/resolve?ref=aipoch/open-science/evo2
GET https://markdownregistry.com/api/v1/blob/95f2a4439715857f726ccb4f1050493fea8a0a547581f695428554513c2b2604