snakemake-workflow-engine SKILL.md skillA

snakemake-workflow-engine from jaechang-hits/sciagent-skills is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.

Install it, pinned
mdr add jaechang-hits/sciagent-skills/snakemake-workflow-engine@git:20260428.81ea2d2

Pins git:20260428.81ea2d2 in mdr.lock. Pin the fingerprint instead.

Audit grade
A, 17 of 17 checks passed
Kind
SKILL.md skill
Repository
jaechang-hits/sciagent-skills
Path
skills/scientific-computing/snakemake-workflow-engine/SKILL.md
Versions recorded
3
Latest version
git:20260428.81ea2d2, committed Apr 28, 2026
First version recorded
Feb 18, 2026
Size
18,852 bytes
Repository stars
381
License
a license file GitHub does not identify

Python-based workflow manager for reproducible, scalable pipelines. Define rules with file-based dependencies; Snakemake resolves execution order and parallelism. Runs local, SLURM, LSF, AWS, GCP via profiles; per-rule conda/Singularity envs. For NGS pipelines, ML training, and multi-step file processing. Use Nextflow for Groovy dataflow or nf-core integration.

Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.

What the file says

# Snakemake — Python Workflow Engine

## Overview

Snakemake is a Python-based workflow management system that scales analyses from laptop to HPC and cloud. Workflows are defined as rules with explicit input/output file dependencies; Snakemake resolves the execution order automatically and runs independent steps in parallel. Rules can call shell commands, Python/R/Julia scripts, or inline Python. Per-rule conda or Singularity environments make workflows fully reproducible. Widely used in bioinformatics for NGS, genome assembly, and variant-calling pipelines.

## When to Use

- Building reproducible multi-step bioinformatics pipelines (align → sort → call variants → annotate)
- Scaling the same workflow from local development to SLURM cluster without code changes
- Processing multiple samples identically using wildcard-based rules
- Managing dependencies automatically — only rerun steps whose inputs changed
- Deploying per-rule conda or Singularity environments for tool isolation
- Generating visual DAGs and dry-run previews before committing computational resources
…

Read the whole file at its exact version.

How to install

The exact contents, by fingerprint
mdr add jaechang-hits/sciagent-skills/snakemake-workflow-engine@sha256:4d0db95dc5471e1f

The line at the top of this page pins the label git:20260428.81ea2d2, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.

Badge

mdr badge

[![mdr](https://markdownregistry.com/badge/art_wpwfk6wqltdssbzi.svg)](https://markdownregistry.com/a/art_wpwfk6wqltdssbzi)

1 badge image fetches in 30 days. What the badge shows.

Versions

The registry has recorded 3 versions of this file, between Feb 18, 2026 and Apr 28, 2026, about one every 34 days.

versioncommittedcommitsizeaudit
git:20260428.81ea2d2 latest2026-04-28 81ea2d2 18,852 BA view · diff
git:20260414.65bebbb2026-04-14 65bebbb 19,010 BA view · diff
git:20260218.8df16942026-02-18 8df1694 18,680 BA view

Audit of the latest version

A  17 of 17 checks passed. Fixed automatic checks with no AI involved, so the same checks give the same answer every run.
  • pass: Frontmatter block present
  • pass: Frontmatter declares a name
  • pass: Frontmatter declares a description
  • pass: Size between 200 bytes and 200 KB (18852 bytes)
  • pass: No zero-width or bidi control characters
  • pass: No instruction hidden inside an HTML comment
  • pass: No link to an exfiltration or paste host
  • pass: No credential-shaped string
  • pass: No instruction to send local credentials anywhere
  • pass: No text hidden with inline styles
  • pass: No prompt-injection phrasing
  • pass: No curl or wget piped into a shell
  • pass: No recursive delete of root, home or parent
  • pass: No instruction to read or print local credentials
  • pass: No base64 blob over 200 characters
  • pass: No link to a raw IP address
  • pass: No script tag

Source

GitHub

jaechang-hits/sciagent-skills · 381 stars · license a license file GitHub does not identify · pushed 2026-10-16 · branch main

API

GET https://markdownregistry.com/api/v1/artifacts/art_wpwfk6wqltdssbzi
GET https://markdownregistry.com/api/v1/resolve?ref=jaechang-hits/sciagent-skills/snakemake-workflow-engine
GET https://markdownregistry.com/api/v1/blob/4d0db95dc5471e1fcd1b5cfd45c432a7c029850046bbfafb353ffbe0b1cc7536

Your AI assistant does the legwork. You hear about the deals worth your word. Hand yours the standing instructions at modelranch.com and it joins the network that reads files like this one.

Guides: the SKILL.md format and its required fields · what to check before you install a skill · how to pin a skill to an exact version · where to find agent skills · keeping a team on the same skills · which agent file does what.

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