encode-database SKILL.md skillA
encode-database from jaechang-hits/sciagent-skills is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.
mdr add jaechang-hits/sciagent-skills/encode-database@git:20260528.3e3f998Pins git:20260528.3e3f998 in mdr.lock. Pin the fingerprint instead.
- Audit grade
- A, 17 of 17 checks passed
- Kind
- SKILL.md skill
- Repository
- jaechang-hits/sciagent-skills
- Path
skills/genomics-bioinformatics/databases/encode-database/SKILL.md- Versions recorded
- 1
- Latest version
- git:20260528.3e3f998, committed May 28, 2026
- Size
- 34,061 bytes
- Repository stars
- 381
- License
- a license file GitHub does not identify
ENCODE Portal REST API for regulatory genomics: TF ChIP-seq, ATAC-seq/DNase-seq peaks, histone marks, and RNA-seq across 1000+ cell types. Search experiments by assay/biosample/target; download BED/bigWig; retrieve SCREEN cCREs by region or gene. Use to annotate variants with regulatory tracks, find open chromatin in a cell type, or fetch peak files for ChIP/ATAC analysis. For regulatory variant scoring use regulomedb-database; for GWAS associations use gwas-database.
Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.
What the file says
# ENCODE Database ## Overview The ENCODE (Encyclopedia of DNA Elements) Project has generated thousands of functional genomics experiments — TF ChIP-seq, ATAC-seq, DNase-seq, histone ChIP-seq, and RNA-seq — across 1000+ human and mouse cell types and tissues. The ENCODE Portal REST API provides structured JSON access to experiment metadata, file download URLs, and SCREEN cCRE (candidate cis-Regulatory Elements) annotations. All data is freely accessible without authentication for most endpoints. ## When to Use - Downloading TF ChIP-seq peak files (BED) for a specific transcription factor and cell type to annotate regulatory regions - Finding ATAC-seq or DNase-seq peaks in a cell type to identify open chromatin regions near a gene of interest - Retrieving cCREs (candidate cis-Regulatory Elements) overlapping a genomic region from ENCODE SCREEN - Building reference regulatory tracks for variant annotation pipelines (e.g., annotating VCF variants against ENCODE peak sets) - Exploring which experiments are available for a biosample (cell line, tissue, developmental stage) before planning a wet-lab experiment …
Read the whole file at its exact version.
How to install
mdr add jaechang-hits/sciagent-skills/encode-database@sha256:21de5a98ef92de4eThe line at the top of this page pins the label git:20260528.3e3f998, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.
[](https://markdownregistry.com/a/art_y62sq4wdy6nrjlk6)
3 badge image fetches in 30 days. What the badge shows.
Versions
The registry has recorded 1 version of this file, committed on May 28, 2026.
Audit of the latest version
- pass: Frontmatter block present
- pass: Frontmatter declares a name
- pass: Frontmatter declares a description
- pass: Size between 200 bytes and 200 KB (34061 bytes)
- pass: No zero-width or bidi control characters
- pass: No instruction hidden inside an HTML comment
- pass: No link to an exfiltration or paste host
- pass: No credential-shaped string
- pass: No instruction to send local credentials anywhere
- pass: No text hidden with inline styles
- pass: No prompt-injection phrasing
- pass: No curl or wget piped into a shell
- pass: No recursive delete of root, home or parent
- pass: No instruction to read or print local credentials
- pass: No base64 blob over 200 characters
- pass: No link to a raw IP address
- pass: No script tag
Source
jaechang-hits/sciagent-skills · 381 stars · license a license file GitHub does not identify · pushed 2026-10-16 · branch main
API
GET https://markdownregistry.com/api/v1/artifacts/art_y62sq4wdy6nrjlk6 GET https://markdownregistry.com/api/v1/resolve?ref=jaechang-hits/sciagent-skills/encode-database GET https://markdownregistry.com/api/v1/blob/21de5a98ef92de4e706d758d9e0fed2a7f1a660e8e2bca743e1d0f135d20f217
Your AI assistant does the legwork. You hear about the deals worth your word. Hand yours the standing instructions at modelranch.com and it joins the network that reads files like this one.
Guides: the SKILL.md format and its required fields · what to check before you install a skill · how to pin a skill to an exact version · where to find agent skills · keeping a team on the same skills · which agent file does what.