arboreto SKILL.md skillA

This file is byte-identical to the first copy the registry indexed. Same content hash, so the same checks give both the same grade.

arboreto from fridrichmethod/awesome-skills is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.

Install it, pinned
mdr add fridrichmethod/awesome-skills/arboreto@v1.3

Pins v1.3 in mdr.lock. Pin the fingerprint instead.

Audit grade
A, 17 of 17 checks passed
Kind
SKILL.md skill
Repository
fridrichmethod/awesome-skills
Path
skills/arboreto/SKILL.md
Versions recorded
4
Latest version
v1.3, committed Oct 4, 2026
First version recorded
May 28, 2026
Size
10,661 bytes
Repository stars
15
License
a license file GitHub does not identify

Infers candidate gene regulatory networks from bulk or single-cell expression data using AertsLab Arboreto GRNBoost2 and GENIE3. Use for transcription factor-target association ranking, compatible Dask execution, sparse expression inputs, and network stability checks.

Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.

What the file says

# Arboreto

## When to use

Use Arboreto to rank candidate regulator-target associations from expression
measurements. GRNBoost2 fits stochastic gradient boosting regressions; GENIE3
fits random forests. Each target is predicted from candidate regulators, excluding
itself. These are observational predictive associations, not proof of direct
binding, activation/repression, or causal regulation.

The latest PyPI release checked is **0.1.6** (2021-02-09). Read the Docs still
labels its documentation 0.1.5; the current GitHub source contains fixes that are
**not in the PyPI wheel**. Do not assume a successful unpinned installation can
run inference. See [compatibility and distribution details](references/distributed_computing.md).

## Installation and compatibility

The following exact stack passed dense and CSC-sparse GRNBoost2, dense GENIE3,
custom GBM/RF, and wrapper smoke tests on macOS arm64 with Python 3.11.11:

```bash
uv venv --python 3.11 .venv-arboreto
uv pip install --python .venv-arboreto/bin/python \
  'arboreto==0.1.6' 'dask[complete]==2024.7.1' 'distributed==2024.7.1' \
  'numpy==1.26.4' 'pandas==2.2.3' 'scikit-learn==1.5.2' 'scipy==1.13.1'
```
…

Read the whole file at its exact version.

How to install

The exact contents, by fingerprint
mdr add fridrichmethod/awesome-skills/arboreto@sha256:38ff6f24b8fd4a86

The line at the top of this page pins the label v1.3, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.

Badge

mdr badge

[![mdr](https://markdownregistry.com/badge/art_6ch3ogl3vyzny4fo.svg)](https://markdownregistry.com/a/art_6ch3ogl3vyzny4fo)

1 badge image fetches in 30 days. What the badge shows.

Versions

The registry has recorded 4 versions of this file, between May 28, 2026 and Oct 4, 2026, about one every 43 days.

versioncommittedcommitsizeaudit
v1.3 latest2026-10-04 abbbdf3 10,661 BA view · diff
v1.12026-09-06 cd40869 9,416 BA view · diff
git:20260614.5d4591c2026-06-14 5d4591c 8,464 BA view · diff
v1.02026-05-28 89ddef6 8,459 BA view

Audit of the latest version

A  17 of 17 checks passed. Fixed automatic checks with no AI involved, so the same checks give the same answer every run.
  • pass: Frontmatter block present
  • pass: Frontmatter declares a name
  • pass: Frontmatter declares a description
  • pass: Size between 200 bytes and 200 KB (10661 bytes)
  • pass: No zero-width or bidi control characters
  • pass: No instruction hidden inside an HTML comment
  • pass: No link to an exfiltration or paste host
  • pass: No credential-shaped string
  • pass: No instruction to send local credentials anywhere
  • pass: No text hidden with inline styles
  • pass: No prompt-injection phrasing
  • pass: No curl or wget piped into a shell
  • pass: No recursive delete of root, home or parent
  • pass: No instruction to read or print local credentials
  • pass: No base64 blob over 200 characters
  • pass: No link to a raw IP address
  • pass: No script tag

Source

GitHub

fridrichmethod/awesome-skills · 15 stars · license a license file GitHub does not identify · pushed 2026-10-18 · branch main

API

GET https://markdownregistry.com/api/v1/artifacts/art_6ch3ogl3vyzny4fo
GET https://markdownregistry.com/api/v1/resolve?ref=fridrichmethod/awesome-skills/arboreto
GET https://markdownregistry.com/api/v1/blob/38ff6f24b8fd4a86e2a57ae7bb7669fe4ce401f7375efcc82a6c004f4c51d344

Your AI assistant does the legwork. You hear about the deals worth your word. Hand yours the standing instructions at modelranch.com and it joins the network that reads files like this one.

Guides: the SKILL.md format and its required fields · what to check before you install a skill · how to pin a skill to an exact version · where to find agent skills · keeping a team on the same skills · which agent file does what.

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Every file in fridrichmethod/awesome-skills

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