design-study SKILL.md skillA

design-study from aperivue/medsci-skills is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.

Install it, pinned
mdr add aperivue/medsci-skills/design-study@git:20260930.c8ed96c

Pins git:20260930.c8ed96c in mdr.lock. Pin the fingerprint instead.

Audit grade
A, 17 of 17 checks passed
Kind
SKILL.md skill
Repository
aperivue/medsci-skills
Path
skills/design-study/SKILL.md
Versions recorded
10
Latest version
git:20260930.c8ed96c, committed Sep 30, 2026
First version recorded
Jul 14, 2026
Size
15,586 bytes
Repository stars
366
License
MIT

Use when checking a radiology or medical AI study design before drafting or submission. Reviews the analysis unit, cohort logic, leakage risks, comparator, validation strategy and reporting-guideline fit. AI-vs-expert benchmarks are /design-ai-benchmarking.

Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.

What the file says

# Design-Study Skill

## Core Review Questions

Always inspect:

1. The exact research question.
2. The analysis unit: patient, lesion, exam, study, phase, report.
3. The index date or decision point.
4. How inclusion and exclusion criteria are applied.
5. Any information leakage.
6. The reference standard or endpoint definition.
7. A clinically meaningful comparator.
8. The validation strategy.
9. The uncertainty reporting required.
10. The best-fitting reporting guideline.
11. Whether exposure/outcome/covariate **definitions are literature-grounded** or invented ad hoc from the data dictionary. If ad hoc, defer to `/define-variables` before drafting Methods.

---

## Standard Output

```text
## Study Design Review
Question: ...
Study type: ...
Analysis unit: ...
Index date / prediction timepoint: ...

### Strengths
- ...

### Major validity risks
1. ...
2. ...

### Minimal fixes
- ...

### Reporting fit
- Recommended guideline: ...

### Decision
- Ready for analysis / Needs redesign / Drafting can proceed with limitations
```
…

Read the whole file at its exact version.

How to install

The exact contents, by fingerprint
mdr add aperivue/medsci-skills/design-study@sha256:ee49cc85fe95901d

The line at the top of this page pins the label git:20260930.c8ed96c, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.

Badge

mdr badge

[![mdr](https://markdownregistry.com/badge/art_al2seqxg6g5c24ii.svg)](https://markdownregistry.com/a/art_al2seqxg6g5c24ii)

2 badge image fetches in 30 days. What the badge shows.

Versions

The registry has recorded 10 versions of this file, between Jul 14, 2026 and Sep 30, 2026, about one every 9 days.

versioncommittedcommitsizeaudit
git:20260930.c8ed96c latest2026-09-30 c8ed96c 15,586 BA view · diff
git:20260930.30387c22026-09-30 30387c2 14,805 BA view · diff
git:20260930.e4f475f2026-09-30 e4f475f 14,810 BA view · diff
git:20260930.c83ad002026-09-30 c83ad00 14,813 BA view · diff
git:20260915.b09a3832026-09-15 b09a383 18,603 BA view · diff
git:20260725.67fd47f2026-07-25 67fd47f 18,884 BA view · diff
git:20260725.13ac0062026-07-25 13ac006 17,637 BA view · diff
git:20260725.58527fd2026-07-25 58527fd 16,485 BA view · diff
git:20260725.a91e0592026-07-25 a91e059 15,702 BA view · diff
git:20260714.90da8412026-07-14 90da841 15,269 BA view

Audit of the latest version

A  17 of 17 checks passed. Fixed automatic checks with no AI involved, so the same checks give the same answer every run.
  • pass: Frontmatter block present
  • pass: Frontmatter declares a name
  • pass: Frontmatter declares a description
  • pass: Size between 200 bytes and 200 KB (15586 bytes)
  • pass: No zero-width or bidi control characters
  • pass: No instruction hidden inside an HTML comment
  • pass: No link to an exfiltration or paste host
  • pass: No credential-shaped string
  • pass: No instruction to send local credentials anywhere
  • pass: No text hidden with inline styles
  • pass: No prompt-injection phrasing
  • pass: No curl or wget piped into a shell
  • pass: No recursive delete of root, home or parent
  • pass: No instruction to read or print local credentials
  • pass: No base64 blob over 200 characters
  • pass: No link to a raw IP address
  • pass: No script tag

Source

GitHub

aperivue/medsci-skills · 366 stars · license MIT · pushed 2026-11-02 · branch main

API

GET https://markdownregistry.com/api/v1/artifacts/art_al2seqxg6g5c24ii
GET https://markdownregistry.com/api/v1/resolve?ref=aperivue/medsci-skills/design-study
GET https://markdownregistry.com/api/v1/blob/ee49cc85fe95901d752d55a9fe7f78de0af3864523fabcc4ef37012135c47b62

Your AI assistant does the legwork. You hear about the deals worth your word. Hand yours the standing instructions at modelranch.com and it joins the network that reads files like this one.

Guides: the SKILL.md format and its required fields · what to check before you install a skill · how to pin a skill to an exact version · where to find agent skills · keeping a team on the same skills · which agent file does what.

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