admet_genetic SKILL.md skillA
admet_genetic from pku-yuangroup/openai4s is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.
mdr add pku-yuangroup/openai4s/admet_genetic@git:20260828.e9753bePins git:20260828.e9753be in mdr.lock. Pin the fingerprint instead.
- Audit grade
- A, 17 of 17 checks passed
- Kind
- SKILL.md skill
- Repository
- pku-yuangroup/openai4s
- Path
skills/admet_genetic/SKILL.md- Versions recorded
- 3
- Latest version
- git:20260828.e9753be, committed Aug 28, 2026
- First version recorded
- Jul 11, 2026
- Size
- 13,642 bytes
- Repository stars
- 662
- License
- MIT
ADMET-guided genetic molecule optimization workflow from seed SMILES; use when the agent needs to build or run an RDKit/SA-Score/ADMET-AI GA pipeline for molecule optimization, enforce molecule lineage logs, render optimization-history HTML dashboards, and write candidate triage reports.
Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.
What the file says
# ADMET Genetic Optimization
Use this skill to build and run a molecular optimization loop from seed SMILES. The target artifact is a ranked set of optimized candidate molecules with auditable lineage, scores, and report artifacts.
The sidecar deliberately does not provide a fixed GA engine. The agent must
assemble and tune mutation, crossover, evaluation, filtering, and selection for
the user's objective. `kernel.py` provides reusable molecule normalization,
ADMET aggregation, lineage validation, and result visualization.
## Special Reminder
In this skill, when see `references/<file_name>.md` is suggested, use host call to retrieval the complementary material.
```python
host.skills.read("admet_genetic", "references/<file_name>.md")
```
## Prerequisites
```bash
conda create -n admet-sa-ga python=3.11 -y
conda activate admet-sa-ga
python -m pip install pandas pyyaml matplotlib rdkit
python -m pip install admet-ai # depends on torch; installation/import may take time
```
After creating the environment, select it with `host.env.use("admet-sa-ga")`
before importing this skill's sidecar. Switching environments restarts the
…Read the whole file at its exact version.
How to install
mdr add pku-yuangroup/openai4s/admet_genetic@sha256:a2b0882670424f37The line at the top of this page pins the label git:20260828.e9753be, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.
[](https://markdownregistry.com/a/art_onswsd54j3j4uli5)
4 badge image fetches in 30 days. What the badge shows.
Versions
The registry has recorded 3 versions of this file, between Jul 11, 2026 and Aug 28, 2026, about one every 24 days.
| version | committed | commit | size | audit | |
|---|---|---|---|---|---|
| git:20260828.e9753be latest | 2026-08-28 | e9753be | 13,642 B | A | view · diff |
| git:20260826.541380e | 2026-08-26 | 541380e | 13,586 B | A | view · diff |
| git:20260711.d39be3d | 2026-07-11 | d39be3d | 8,824 B | A | view |
Audit of the latest version
- pass: Frontmatter block present
- pass: Frontmatter declares a name
- pass: Frontmatter declares a description
- pass: Size between 200 bytes and 200 KB (13642 bytes)
- pass: No zero-width or bidi control characters
- pass: No instruction hidden inside an HTML comment
- pass: No link to an exfiltration or paste host
- pass: No credential-shaped string
- pass: No instruction to send local credentials anywhere
- pass: No text hidden with inline styles
- pass: No prompt-injection phrasing
- pass: No curl or wget piped into a shell
- pass: No recursive delete of root, home or parent
- pass: No instruction to read or print local credentials
- pass: No base64 blob over 200 characters
- pass: No link to a raw IP address
- pass: No script tag
Source
pku-yuangroup/openai4s · 662 stars · license MIT · pushed 2026-11-03 · branch main
API
GET https://markdownregistry.com/api/v1/artifacts/art_onswsd54j3j4uli5 GET https://markdownregistry.com/api/v1/resolve?ref=pku-yuangroup/openai4s/admet_genetic GET https://markdownregistry.com/api/v1/blob/a2b0882670424f3796851fae0f365707a8f7022eeef53afdc8e5e50c37681662
Your AI assistant does the legwork. You hear about the deals worth your word. Hand yours the standing instructions at modelranch.com and it joins the network that reads files like this one.
Guides: the SKILL.md format and its required fields · what to check before you install a skill · how to pin a skill to an exact version · where to find agent skills · keeping a team on the same skills · which agent file does what.