hypothesis-generation SKILL.md skillA

hypothesis-generation from foryourhealth111-pixel/vibe-skills is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.

Install it, pinned
mdr add foryourhealth111-pixel/vibe-skills/hypothesis-generation@git:20260430.453068c

Pins git:20260430.453068c in mdr.lock. Pin the fingerprint instead.

Audit grade
A, 17 of 17 checks passed
Kind
SKILL.md skill
Repository
foryourhealth111-pixel/vibe-skills
Path
bundled/skills/hypothesis-generation/SKILL.md
Versions recorded
3
Latest version
git:20260430.453068c, committed Apr 30, 2026
First version recorded
Mar 3, 2026
Size
12,462 bytes
Repository stars
3,788
License
Apache-2.0

Structured hypothesis formulation from observations. Use when you have experimental observations or data and need to formulate testable hypotheses with predictions, propose mechanisms, and design experiments to test them. Also owns explicit HypoGeniC-style or automated LLM-driven hypothesis generation/testing requests inside this single skill. For open-ended ideation use scientific-brainstorming.

Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.

What the file says

# Scientific Hypothesis Generation

## Overview

Hypothesis generation is a systematic process for developing testable explanations. Formulate evidence-based hypotheses from observations, design experiments, explore competing explanations, and develop predictions. Apply this skill for scientific inquiry across domains.

## When to Use This Skill

This skill should be used when:
- Developing hypotheses from observations or preliminary data
- Designing experiments to test scientific questions
- Exploring competing explanations for phenomena
- Formulating testable predictions for research
- Conducting literature-based hypothesis generation
- Running a lightweight HypoGeniC-style workflow when the user explicitly asks for automated hypothesis generation/testing
- Planning mechanistic studies across scientific domains

## Outputs

Produce a structured hypothesis report when useful:

- Core observation or anomaly to explain
- Competing mechanistic hypotheses
- Testable predictions for each hypothesis
- Minimal validation experiments or studies
- Decision criteria for supporting, revising, or rejecting each hypothesis
…

Read the whole file at its exact version.

How to install

The exact contents, by fingerprint
mdr add foryourhealth111-pixel/vibe-skills/hypothesis-generation@sha256:17739ba3f71f36cb

The line at the top of this page pins the label git:20260430.453068c, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.

Badge

mdr badge

[![mdr](https://markdownregistry.com/badge/art_orzvm74wamhhxhac.svg)](https://markdownregistry.com/a/art_orzvm74wamhhxhac)

2 badge image fetches in 30 days. What the badge shows.

Versions

The registry has recorded 3 versions of this file, between Mar 3, 2026 and Apr 30, 2026, about one every 29 days.

versioncommittedcommitsizeaudit
git:20260430.453068c latest2026-04-30 453068c 12,462 BA view · diff
git:20260430.01248142026-04-30 0124814 12,323 BA view · diff
git:20260303.491ea972026-03-03 491ea97 13,846 BA view

Audit of the latest version

A  17 of 17 checks passed. Fixed automatic checks with no AI involved, so the same checks give the same answer every run.
  • pass: Frontmatter block present
  • pass: Frontmatter declares a name
  • pass: Frontmatter declares a description
  • pass: Size between 200 bytes and 200 KB (12462 bytes)
  • pass: No zero-width or bidi control characters
  • pass: No instruction hidden inside an HTML comment
  • pass: No link to an exfiltration or paste host
  • pass: No credential-shaped string
  • pass: No instruction to send local credentials anywhere
  • pass: No text hidden with inline styles
  • pass: No prompt-injection phrasing
  • pass: No curl or wget piped into a shell
  • pass: No recursive delete of root, home or parent
  • pass: No instruction to read or print local credentials
  • pass: No base64 blob over 200 characters
  • pass: No link to a raw IP address
  • pass: No script tag

Source

GitHub

foryourhealth111-pixel/vibe-skills · 3,788 stars · license Apache-2.0 · pushed 2026-10-31 · branch main

API

GET https://markdownregistry.com/api/v1/artifacts/art_orzvm74wamhhxhac
GET https://markdownregistry.com/api/v1/resolve?ref=foryourhealth111-pixel/vibe-skills/hypothesis-generation
GET https://markdownregistry.com/api/v1/blob/17739ba3f71f36cb82920d3bfbd648b0d8fb0055f889717f559016f240becbb5

Your AI assistant does the legwork. You hear about the deals worth your word. Hand yours the standing instructions at modelranch.com and it joins the network that reads files like this one.

Guides: the SKILL.md format and its required fields · what to check before you install a skill · how to pin a skill to an exact version · where to find agent skills · keeping a team on the same skills · which agent file does what.

More from foryourhealth111-pixel/vibe-skills

vibe SKILL.md skill
foryourhealth111-pixel/vibe-skills · SKILL.md · Vibe Code Orchestrator (VCO) is a governed runtime entry that freezes requirements, bounds execution, and enforces…
git:20261016.36638e0 · audit A · 3,788 stars
skill-creator SKILL.md skill
foryourhealth111-pixel/vibe-skills · bundled/skills/.system/skill-creator/SKILL.md · Guide for creating effective skills. This skill should be used when users want to create a new skill (or update an…
git:20260226.1632f40 · audit A · 3,788 stars
skill-installer SKILL.md skill
foryourhealth111-pixel/vibe-skills · bundled/skills/.system/skill-installer/SKILL.md · Install Codex skills into $CODEX_HOME/skills from a curated list or a GitHub repo path. Use when a user asks to list…
git:20260226.1632f40 · audit A · 3,788 stars
LQF_Machine_Learning_Expert_Guide SKILL.md skill
foryourhealth111-pixel/vibe-skills · bundled/skills/LQF_Machine_Learning_Expert_Guide/SKILL.md · LQF Machine Learning Expert Guide - Routed skill for ML/Statistical Modeling with Critical Discussion Mode. Triggers…
v2.0.0 · audit A · 3,788 stars
adaptyv SKILL.md skill
foryourhealth111-pixel/vibe-skills · bundled/skills/adaptyv/SKILL.md · Cloud laboratory platform for automated protein testing and validation. Use when designing proteins and needing…
git:20260226.1632f40 · audit A · 3,788 stars
aeon SKILL.md skill
foryourhealth111-pixel/vibe-skills · bundled/skills/aeon/SKILL.md · This skill should be used for time series machine learning tasks including classification, regression, clustering…
git:20260226.1632f40 · audit A · 3,788 stars
algorithmic-art SKILL.md skill
foryourhealth111-pixel/vibe-skills · bundled/skills/algorithmic-art/SKILL.md · Creating algorithmic art using p5.js with seeded randomness and interactive parameter exploration. Use this when users…
git:20260226.1632f40 · audit B · 3,788 stars
alpha-vantage SKILL.md skill
foryourhealth111-pixel/vibe-skills · bundled/skills/alpha-vantage/SKILL.md · Access real-time and historical stock market data, forex rates, cryptocurrency prices, commodities, economic…
git:20260303.491ea97 · audit A · 3,788 stars
architecture-patterns SKILL.md skill
foryourhealth111-pixel/vibe-skills · bundled/skills/architecture-patterns/SKILL.md · Implement proven backend architecture patterns including Clean Architecture, Hexagonal Architecture, and Domain-Driven…
git:20260226.1632f40 · audit A · 3,788 stars
astropy SKILL.md skill
foryourhealth111-pixel/vibe-skills · bundled/skills/astropy/SKILL.md · Comprehensive Python library for astronomy and astrophysics. This skill should be used when working with astronomical…
git:20260303.491ea97 · audit A · 3,788 stars
autonomous-builder SKILL.md skill
foryourhealth111-pixel/vibe-skills · bundled/skills/autonomous-builder/SKILL.md · Full-stack software development agent for design, implementation, testing, and deployment. Use when the user explicitly…
v1.0.0 · audit A · 3,788 stars
bio-database-evidence SKILL.md skill
foryourhealth111-pixel/vibe-skills · bundled/skills/bio-database-evidence/SKILL.md · Unified biological database evidence owner. Use for gene annotation, variant clinical significance, cancer mutation…
git:20260430.784fe8b · audit A · 3,788 stars

Every file in foryourhealth111-pixel/vibe-skills

Other files named hypothesis-generation

hypothesis-generation SKILL.md skill
k-dense-ai/scientific-agent-skills · skills/hypothesis-generation/SKILL.md · Formulates evidence-bounded scientific questions, candidate hypotheses, rival explanations, causal or associational…
v2.4 · audit A · 55,514 stars
hypothesis-generation SKILL.md skill
oleafly/oleafly · src-tauri/resources/skills/hypothesis-generation/SKILL.md · Formulate evidence-bounded scientific questions, candidate hypotheses, rival explanations, causal or associational…
v2.2 · audit A · 986 stars
hypothesis-generation SKILL.md skill
jaechang-hits/sciagent-skills · skills/scientific-writing/hypothesis-generation/SKILL.md · Structured hypothesis formulation: turn observations into testable hypotheses with predictions, propose mechanisms…
git:20260528.a0c28a2 · audit A · 384 stars
hypothesis-generation SKILL.md skill
apatheticmioz/castor · skills/hypothesis-generation/SKILL.md · Structured root-cause and optimization hypothesis generation — gather evidence, state ranked falsifiable…
git:20261026.587ad32 · audit A · 12 stars

Browse by kind, by grade A, or by owner.