hypothesis-generation SKILL.md skillA

hypothesis-generation from k-dense-ai/scientific-agent-skills is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.

Install it, pinned
mdr add k-dense-ai/scientific-agent-skills/hypothesis-generation@v2.4

Pins v2.4 in mdr.lock. Pin the fingerprint instead.

Audit grade
A, 17 of 17 checks passed
Kind
SKILL.md skill
Repository
k-dense-ai/scientific-agent-skills
Path
skills/hypothesis-generation/SKILL.md
Versions recorded
7
Latest version
v2.4, committed Oct 1, 2026
First version recorded
Jun 11, 2026
Size
16,622 bytes
Repository stars
53,159
License
MIT

Formulates evidence-bounded scientific questions, candidate hypotheses, rival explanations, causal or associational claims, discriminating predictions, measurements, and preregistration-ready analysis plans. Used when turning observations or preliminary findings into transparent, testable research plans without treating hypotheses as facts.

Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.

What the file says

# Scientific Hypothesis Generation

Turn an observation into a transparent set of candidate explanations and tests. A hypothesis is a proposal to be challenged, not a finding, fact, diagnosis, or recommendation.

## Non-negotiable boundaries

Before using unpublished, sensitive, controlled, personal, proprietary, export-controlled, or security-relevant material:

1. Confirm authorization and the applicable institutional, funder, publisher, data-use, privacy, and AI policies.
2. Keep the material local unless an authorized human explicitly approves a named external destination and data scope.
3. Minimize inputs. Do not place sensitive or unpublished data in web searches or external AI systems without authorization.
4. Stop at the appropriate human, animal, biosafety, dual-use, data-governance, or regulatory gate.

Never:

- present a hypothesis, mechanism, causal effect, citation, or apparent pattern as established evidence;
- claim novelty because a quick search found nothing;
- infer causation from association, temporal order alone, predictive accuracy, or model output;
- supply patient-specific diagnosis, treatment, dose, prognosis, or other clinical advice;
…

Read the whole file at its exact version.

How to install

The exact contents, by fingerprint
mdr add k-dense-ai/scientific-agent-skills/hypothesis-generation@sha256:5bccec0437d96d61

The line at the top of this page pins the label v2.4, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.

Badge

mdr badge

[![mdr](https://markdownregistry.com/badge/art_42a3k23vhjhtt3y6.svg)](https://markdownregistry.com/a/art_42a3k23vhjhtt3y6)

4 badge image fetches in 30 days. What the badge shows.

Versions

The registry has recorded 7 versions of this file, between Jun 11, 2026 and Oct 1, 2026, about one every 19 days.

versioncommittedcommitsizeaudit
v2.4 latest2026-10-01 a92663a 16,622 BA view · diff
v2.32026-09-30 ce9e6e9 16,120 BA view · diff
v2.22026-09-02 1e5eeff 15,725 BA view · diff
v2.12026-07-26 2f2022d 14,767 BA view · diff
v2.02026-07-24 f375cf7 14,767 BA view · diff
git:20260721.831d49e2026-07-21 831d49e 14,222 BA view · diff
git:20260611.c1150bd2026-06-11 c1150bd 14,222 BA view

Audit of the latest version

A  17 of 17 checks passed. Fixed automatic checks with no AI involved, so the same checks give the same answer every run.
  • pass: Frontmatter block present
  • pass: Frontmatter declares a name
  • pass: Frontmatter declares a description
  • pass: Size between 200 bytes and 200 KB (16622 bytes)
  • pass: No zero-width or bidi control characters
  • pass: No instruction hidden inside an HTML comment
  • pass: No link to an exfiltration or paste host
  • pass: No credential-shaped string
  • pass: No instruction to send local credentials anywhere
  • pass: No text hidden with inline styles
  • pass: No prompt-injection phrasing
  • pass: No curl or wget piped into a shell
  • pass: No recursive delete of root, home or parent
  • pass: No instruction to read or print local credentials
  • pass: No base64 blob over 200 characters
  • pass: No link to a raw IP address
  • pass: No script tag

Source

GitHub

k-dense-ai/scientific-agent-skills · 53,159 stars · license MIT · pushed 2026-10-19 · branch main

API

GET https://markdownregistry.com/api/v1/artifacts/art_42a3k23vhjhtt3y6
GET https://markdownregistry.com/api/v1/resolve?ref=k-dense-ai/scientific-agent-skills/hypothesis-generation
GET https://markdownregistry.com/api/v1/blob/5bccec0437d96d61821ec2095e7e32b61e8634cd8c02f11f42da953121e92719

Your AI assistant does the legwork. You hear about the deals worth your word. Hand yours the standing instructions at modelranch.com and it joins the network that reads files like this one.

Guides: the SKILL.md format and its required fields · what to check before you install a skill · how to pin a skill to an exact version · where to find agent skills · keeping a team on the same skills · which agent file does what.

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Every file in k-dense-ai/scientific-agent-skills

Other files named hypothesis-generation

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v2.2 · audit A · 258 stars

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