anndata SKILL.md skillA

anndata from k-dense-ai/scientific-agent-skills is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.

Install it, pinned
mdr add k-dense-ai/scientific-agent-skills/anndata@v1.4

Pins v1.4 in mdr.lock. Pin the fingerprint instead.

Audit grade
A, 17 of 17 checks passed
Kind
SKILL.md skill
Repository
k-dense-ai/scientific-agent-skills
Path
skills/anndata/SKILL.md
Versions recorded
6
Latest version
v1.4, committed Oct 1, 2026
First version recorded
May 27, 2026
Size
15,751 bytes
Repository stars
53,159
License
MIT

Handles annotated matrices in single-cell analysis, .h5ad and Zarr files, and integration with the scverse ecosystem. This is the data format skill—for analysis workflows use scanpy; for probabilistic models use scvi-tools; for population-scale queries use cellxgene-census.

Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.

What the file says

# AnnData

## Overview

AnnData is a Python package for handling annotated data matrices, storing experimental measurements (X) alongside observation metadata (obs), variable metadata (var), and multi-dimensional annotations (obsm, varm, obsp, varp, uns). Originally designed for single-cell genomics through Scanpy, it now serves as a general-purpose framework for any annotated data requiring efficient storage, manipulation, and analysis.

## When to Use This Skill

Use this skill when:
- Creating, reading, or writing AnnData objects
- Working with h5ad, zarr, or other genomics data formats
- Performing single-cell RNA-seq analysis
- Managing large datasets with sparse matrices or backed mode
- Concatenating multiple datasets or experimental batches
- Subsetting, filtering, or transforming annotated data
- Integrating with scanpy, scvi-tools, or other scverse ecosystem tools

## Installation

Targets AnnData 0.13.4 (current PyPI release reviewed 2026-09-30), requiring Python
3.12+. Small synthetic checks cover dense/sparse matrices, native I/O, metadata,
concatenation, and lazy reads. File paths, biological analysis, remote stores, and
…

Read the whole file at its exact version.

How to install

The exact contents, by fingerprint
mdr add k-dense-ai/scientific-agent-skills/anndata@sha256:a619c4088e1be6f6

The line at the top of this page pins the label v1.4, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.

Badge

mdr badge

[![mdr](https://markdownregistry.com/badge/art_x52inwc5thlpp3qe.svg)](https://markdownregistry.com/a/art_x52inwc5thlpp3qe)

4 badge image fetches in 30 days. What the badge shows.

Versions

The registry has recorded 6 versions of this file, between May 27, 2026 and Oct 1, 2026, about one every 25 days.

versioncommittedcommitsizeaudit
v1.4 latest2026-10-01 a92663a 15,751 BA view · diff
v1.32026-09-30 ce9e6e9 13,307 BA view · diff
v1.22026-09-02 1e5eeff 12,883 BA view · diff
v1.12026-07-26 b085e11 11,926 BA view · diff
git:20260611.1b8fae32026-06-11 1b8fae3 11,931 BA view · diff
v1.02026-05-27 0936740 10,912 BA view

Audit of the latest version

A  17 of 17 checks passed. Fixed automatic checks with no AI involved, so the same checks give the same answer every run.
  • pass: Frontmatter block present
  • pass: Frontmatter declares a name
  • pass: Frontmatter declares a description
  • pass: Size between 200 bytes and 200 KB (15751 bytes)
  • pass: No zero-width or bidi control characters
  • pass: No instruction hidden inside an HTML comment
  • pass: No link to an exfiltration or paste host
  • pass: No credential-shaped string
  • pass: No instruction to send local credentials anywhere
  • pass: No text hidden with inline styles
  • pass: No prompt-injection phrasing
  • pass: No curl or wget piped into a shell
  • pass: No recursive delete of root, home or parent
  • pass: No instruction to read or print local credentials
  • pass: No base64 blob over 200 characters
  • pass: No link to a raw IP address
  • pass: No script tag

Source

GitHub

k-dense-ai/scientific-agent-skills · 53,159 stars · license MIT · pushed 2026-10-19 · branch main

API

GET https://markdownregistry.com/api/v1/artifacts/art_x52inwc5thlpp3qe
GET https://markdownregistry.com/api/v1/resolve?ref=k-dense-ai/scientific-agent-skills/anndata
GET https://markdownregistry.com/api/v1/blob/a619c4088e1be6f6feaa5838c63ff8c4381fa21b4adee2a9276aa61464f3a034

Your AI assistant does the legwork. You hear about the deals worth your word. Hand yours the standing instructions at modelranch.com and it joins the network that reads files like this one.

Guides: the SKILL.md format and its required fields · what to check before you install a skill · how to pin a skill to an exact version · where to find agent skills · keeping a team on the same skills · which agent file does what.

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Every file in k-dense-ai/scientific-agent-skills

Other files named anndata

anndata SKILL.md skill
aicodedecode/awesome-muse-skills · skills-imported/anndata/SKILL.md · This skill should be used when working with annotated data matrices in Python, particularly for single-cell genomics…
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anndata SKILL.md skill
fridrichmethod/awesome-skills · skills/anndata/SKILL.md · Handles annotated matrices in single-cell analysis, .h5ad and Zarr files, and integration with the scverse ecosystem…
v1.4 · audit A · 15 stars
anndata SKILL.md skill
marielynneblock/arcanum-artifex · skills/scientific/anndata/SKILL.md · Data structure for annotated matrices in single-cell analysis. Use when working with .h5ad files or integrating with…
git:20260710.0115f49 · audit A · 4 stars

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