Home / ammawla / encode-toolkit · skills/gtex-expression/SKILL.md · GitHub

gtex-expression skillA

gtex-expression is agent-read markdown (skill) from ammawla/encode-toolkit: Guide for integrating GTEx tissue expression data with ENCODE regulatory elements. Use when users need to check if a gene is expressed in a tissue, correlate regulatory elements with expression, or validate ENCODE findings against GTEx. Trigger on: GTEx, tissue expression, gene expression levels, expression atlas, eQTL, tissue-specific expression, TPM values..

Indexed from public GitHub and served as immutable, content-addressed versions. Install it pinned to an exact SHA-256 with the mdr CLI, and every file is verified against the hash recorded here before it reaches your agent. The deterministic audit below grades the latest version, and the same file always earns the same grade.

What the file says

# Integrating GTEx Tissue Expression with ENCODE Regulatory Data

Use GTEx gene expression across 54 human tissues to validate ENCODE regulatory element activity, establish enhancer-gene links, and provide tissue-specific expression context for functional genomics findings.

## Scientific Rationale

**The question**: "Is the gene near my ENCODE regulatory element actually expressed in the tissue where the element is active?"

ENCODE catalogs where regulatory elements exist (enhancers, promoters, insulators) but does not directly measure gene expression across a broad tissue panel. GTEx (Genotype-Tissue Expression) fills this gap by providing RNA-seq-based gene expression measurements across 54 human tissues from ~1,000 post-mortem donors. Integrating the two answers a fundamental question: does the regulatory landscape match the transcriptional output?
…

Read the whole file at its exact version.

How to install

Latest version
mdr add ammawla/encode-toolkit/gtex-expression@git:20260920.6050003
Exact content
mdr add ammawla/encode-toolkit/gtex-expression@sha256:3da4b73a66102cbb

Pin to a label to follow the author's releases, or to a sha256 to freeze the exact bytes forever. Either way the resolved hash is written to mdr.lock, and mdr install reproduces it on any machine.

Badge

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Versions

versioncommittedcommitsizeaudit
git:20260920.6050003 latest2026-09-20 6050003 19,715 BA view · diff
git:20260920.992a8072026-09-20 992a807 19,450 BA view · diff
git:20260312.be327062026-03-12 be32706 19,460 BA view · diff
git:20260308.ca46af52026-03-08 ca46af5 19,471 BA view

Audit of the latest version

A  17 of 17 checks passed. Deterministic, no model, same answer every run.
  • pass: Frontmatter block present
  • pass: Frontmatter declares a name
  • pass: Frontmatter declares a description
  • pass: Size between 200 bytes and 200 KB (19715 bytes)
  • pass: No zero-width or bidi control characters
  • pass: No instruction hidden inside an HTML comment
  • pass: No link to an exfiltration or paste host
  • pass: No credential-shaped string
  • pass: No instruction to send local credentials anywhere
  • pass: No text hidden with inline styles
  • pass: No prompt-injection phrasing
  • pass: No curl or wget piped into a shell
  • pass: No recursive delete of root, home or parent
  • pass: No instruction to read or print local credentials
  • pass: No base64 blob over 200 characters
  • pass: No link to a raw IP address
  • pass: No script tag

Source

GitHub

ammawla/encode-toolkit · 20 stars · license AGPL-3.0 · pushed 2026-09-21 · branch main

API

GET https://markdownregistry.com/api/v1/artifacts/art_x63s3ccim64lbi6c
GET https://markdownregistry.com/api/v1/resolve?ref=ammawla/encode-toolkit/gtex-expression
GET https://markdownregistry.com/api/v1/blob/3da4b73a66102cbbd244e452d11addef6b7465cc6b3224bdbfb21e83fe8de735

Your agent does the legwork. You hear about the deals worth your word. Hand yours the standing instructions at modelranch.com and it joins the network that reads files like this one.

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Other files named gtex-expression

gtex-expression skill
ammawla/encode-toolkit · plugin/skills/gtex-expression/SKILL.md · Guide for integrating GTEx tissue expression data with ENCODE regulatory elements. Use when users need to check if a…
git:20260312.665e731 · audit A · 20 stars

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