primekg SKILL.md skillA

primekg from k-dense-ai/scientific-agent-skills is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.

Install it, pinned
mdr add k-dense-ai/scientific-agent-skills/primekg@v1.4

Pins v1.4 in mdr.lock. Pin the fingerprint instead.

Audit grade
A, 17 of 17 checks passed
Kind
SKILL.md skill
Repository
k-dense-ai/scientific-agent-skills
Path
skills/primekg/SKILL.md
Versions recorded
6
Latest version
v1.4, committed Oct 1, 2026
First version recorded
Jun 11, 2026
Size
9,659 bytes
Repository stars
56,497
License
MIT

Queries a pinned Precision Medicine Knowledge Graph (PrimeKG) CSV for typed gene, drug, disease, and phenotype nodes, direct associations, disease context, and one- or two-hop paths. Use for PrimeKG reproducibility, biological association lookup, and hypothesis generation with relation and data provenance preserved.

Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.

What the file says

# PrimeKG Knowledge Graph

## When to use

Use for reproducing PrimeKG analyses, resolving entities in a specific graph artifact,
or exploring recorded gene, drug, disease, phenotype, anatomy, and pathway associations.
A path supports a research hypothesis; it does not establish causality, treatment efficacy,
a prescribing recommendation, or a diagnostic conclusion.

[PrimeKG upstream](https://github.com/mims-harvard/PrimeKG) now recommends OptimusKG for
new work. This skill remains scoped to PrimeKG CSVs; the helper is not an OptimusKG client.
Published PrimeKG integrates 20 resources, with approximately 129,000 nodes and
4.05 million undirected relationships. CSVs contain reverse rows, so row counts differ
from distinct undirected relationship counts. Count the actual pinned artifact.

## 1. Pin and verify the input

The [official dataset](https://doi.org/10.7910/DVN/IXA7BM) remained **V2.1**, published
2022-05-02, at the 2026-10-01 review. Its `kg.csv` has Dataverse file ID **6180620**,
size **981751236 bytes**, and provider MD5 **aac8191d4fbc5bf09cdf8c3c78b4e75f**.
The record declares **CC0 1.0**; upstream construction code is MIT. These are distinct
…

Read the whole file at its exact version.

How to install

The exact contents, by fingerprint
mdr add k-dense-ai/scientific-agent-skills/primekg@sha256:b20698944fa51b28

The line at the top of this page pins the label v1.4, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.

Badge

mdr badge

[![mdr](https://markdownregistry.com/badge/art_73qio4lgfz5fgxqr.svg)](https://markdownregistry.com/a/art_73qio4lgfz5fgxqr)

4 badge image fetches in 30 days. What the badge shows.

Versions

The registry has recorded 6 versions of this file, between Jun 11, 2026 and Oct 1, 2026, about one every 22 days.

versioncommittedcommitsizeaudit
v1.4 latest2026-10-01 a92663a 9,659 BA view · diff
v1.32026-09-30 ce9e6e9 5,488 BA view · diff
v1.22026-09-02 1e5eeff 4,954 BA view · diff
v1.12026-07-28 4fb7e0b 3,996 BA view · diff
v1.02026-07-26 b085e11 3,836 BA view · diff
git:20260611.1b8fae32026-06-11 1b8fae3 3,841 BA view

Audit of the latest version

A  17 of 17 checks passed. Fixed automatic checks with no AI involved, so the same checks give the same answer every run.
  • pass: Frontmatter block present
  • pass: Frontmatter declares a name
  • pass: Frontmatter declares a description
  • pass: Size between 200 bytes and 200 KB (9659 bytes)
  • pass: No zero-width or bidi control characters
  • pass: No instruction hidden inside an HTML comment
  • pass: No link to an exfiltration or paste host
  • pass: No credential-shaped string
  • pass: No instruction to send local credentials anywhere
  • pass: No text hidden with inline styles
  • pass: No prompt-injection phrasing
  • pass: No curl or wget piped into a shell
  • pass: No recursive delete of root, home or parent
  • pass: No instruction to read or print local credentials
  • pass: No base64 blob over 200 characters
  • pass: No link to a raw IP address
  • pass: No script tag

Source

GitHub

k-dense-ai/scientific-agent-skills · 56,497 stars · license MIT · pushed 2026-11-02 · branch main

API

GET https://markdownregistry.com/api/v1/artifacts/art_73qio4lgfz5fgxqr
GET https://markdownregistry.com/api/v1/resolve?ref=k-dense-ai/scientific-agent-skills/primekg
GET https://markdownregistry.com/api/v1/blob/b20698944fa51b287a13e7dc22ac033b83836b73614a21cff725ad7d6d807226

Your AI assistant does the legwork. You hear about the deals worth your word. Hand yours the standing instructions at modelranch.com and it joins the network that reads files like this one.

Guides: the SKILL.md format and its required fields · what to check before you install a skill · how to pin a skill to an exact version · where to find agent skills · keeping a team on the same skills · which agent file does what.

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