bio-comparative-genomics-hgt-detection SKILL.md skillA
bio-comparative-genomics-hgt-detection from pku-yuangroup/openai4s is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.
mdr add pku-yuangroup/openai4s/bio-comparative-genomics-hgt-detection@git:20260821.2d1b678Pins git:20260821.2d1b678 in mdr.lock. Pin the fingerprint instead.
- Audit grade
- A, 17 of 17 checks passed
- Kind
- SKILL.md skill
- Repository
- pku-yuangroup/openai4s
- Path
skills/bioskills/bio-comparative-genomics-hgt-detection/SKILL.md- Versions recorded
- 1
- Latest version
- git:20260821.2d1b678, committed Aug 21, 2026
- Size
- 34,375 bytes
- Repository stars
- 662
- License
- MIT
Detect horizontal gene transfer (HGT / LGT) using compositional methods (GC%, codon usage, tetranucleotide z-scores via SIGI-HMM, AlienHunter, IslandViewer 4, IslandPath-DIMOB), phylogenetic-incongruence methods (AvP, HGTphyloDetect, ALE / GeneRax / AleRax reconciliation, RANGER-DTL), and BLAST-distribution methods (HGTector v2, DarkHorse, Alien Index). Use when screening prokaryote genomes for genomic islands and HGT events, distinguishing HGT from incomplete lineage sorting / differential…
Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.
What the file says
## Version Compatibility Reference examples tested with: HGTector 2.0b3+, AvP 1.0.4+, HGTphyloDetect 1.0+, ALE 1.0+ (ssolo/ALE github), GeneRax 2.1.3+, AleRax 1.2.0+ (Morel 2024), RANGER-DTL 2.0+, IslandViewer 4 (web), mobileOG-db 1.0+, MetaCHIP 1.10+, IQ-TREE 2.3.6+, BioPython 1.84+, DIAMOND 2.1.10+. Open Tree of Life and NCBI Taxonomy reference databases updated 2024-Q3 minimum for HGTector/AvP. Before using code patterns, verify installed versions match. If versions differ: - Python: `pip show hgtector` then `hgtector search --help` - CLI: `ALEml_undated --help`, `generax --help`, `alerax --help` - DB: `hgtector database --check` for taxonomy version If code throws `Taxonomy ID not found`, `database version mismatch`, or `KeyError` on NCBI taxids, refresh the local taxonomy dump (NCBI updates monthly). ALE/GeneRax expect newick gene trees with bootstraps; AleRax expects gene-tree distributions (uniform bootstrap samples or UFBoot trees). # Horizontal Gene Transfer Detection …
Read the whole file at its exact version.
How to install
mdr add pku-yuangroup/openai4s/bio-comparative-genomics-hgt-detection@sha256:06931f0cfbb6dadbThe line at the top of this page pins the label git:20260821.2d1b678, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.
[](https://markdownregistry.com/a/art_eswj4xnrao55pzlj)
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Versions
The registry has recorded 1 version of this file, committed on Aug 21, 2026.
Audit of the latest version
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- pass: Frontmatter declares a name
- pass: Frontmatter declares a description
- pass: Size between 200 bytes and 200 KB (34375 bytes)
- pass: No zero-width or bidi control characters
- pass: No instruction hidden inside an HTML comment
- pass: No link to an exfiltration or paste host
- pass: No credential-shaped string
- pass: No instruction to send local credentials anywhere
- pass: No text hidden with inline styles
- pass: No prompt-injection phrasing
- pass: No curl or wget piped into a shell
- pass: No recursive delete of root, home or parent
- pass: No instruction to read or print local credentials
- pass: No base64 blob over 200 characters
- pass: No link to a raw IP address
- pass: No script tag
Source
pku-yuangroup/openai4s · 662 stars · license MIT · pushed 2026-11-03 · branch main
API
GET https://markdownregistry.com/api/v1/artifacts/art_eswj4xnrao55pzlj GET https://markdownregistry.com/api/v1/resolve?ref=pku-yuangroup/openai4s/bio-comparative-genomics-hgt-detection GET https://markdownregistry.com/api/v1/blob/06931f0cfbb6dadb72731dfab1565745232f484bd78ee11da1a2b1d1c1923ec2
Your AI assistant does the legwork. You hear about the deals worth your word. Hand yours the standing instructions at modelranch.com and it joins the network that reads files like this one.
Guides: the SKILL.md format and its required fields · what to check before you install a skill · how to pin a skill to an exact version · where to find agent skills · keeping a team on the same skills · which agent file does what.