neuropixels-analysis SKILL.md skillA

neuropixels-analysis from k-dense-ai/scientific-agent-skills is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.

Install it, pinned
mdr add k-dense-ai/scientific-agent-skills/neuropixels-analysis@v2.6

Pins v2.6 in mdr.lock. Pin the fingerprint instead.

Audit grade
A, 17 of 17 checks passed
Kind
SKILL.md skill
Repository
k-dense-ai/scientific-agent-skills
Path
skills/neuropixels-analysis/SKILL.md
Versions recorded
7
Latest version
v2.6, committed Oct 1, 2026
First version recorded
Jun 11, 2026
Size
20,153 bytes
Repository stars
53,159
License
MIT

Analyzes Neuropixels extracellular recordings end-to-end with SpikeInterface. Covers loading SpikeGLX/Open Ephys/NWB data, preprocessing, drift/motion correction, Kilosort4 (and CPU) spike sorting, quality metrics, and unit curation (threshold-based, model-based UnitRefine, and AI-assisted visual review). Use when working with Neuropixels 1.0/2.0 recordings, spike sorting, or extracellular electrophysiology analysis.

Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.

What the file says

# Neuropixels Data Analysis

## Overview

Toolkit for analyzing Neuropixels high-density neural recordings using current best
practices from [SpikeInterface](https://spikeinterface.readthedocs.io/), the Allen
Institute, and the International Brain Laboratory (IBL). It covers the full workflow from
raw data to reviewed, curated units. Targets SpikeInterface 0.105.0,
ProbeInterface 0.4.0 and Neo 0.14.5 (reviewed 2026-10-01). Synthetic tests cover
recording contracts, preprocessing, analyzers, metrics and exports; real acquisition
files, native sorters, GPU execution and pretrained models remain illustrative.

All examples use the real SpikeInterface API (`spikeinterface.full as si`) plus the
companion curation module (`spikeinterface.curation as sc`). The skill ships runnable
scripts in `scripts/` and a copy-and-edit template in `assets/` that implement this
workflow directly on top of SpikeInterface — there is no separate package to install
beyond the dependencies listed under [Installation](#installation).

## When to Use This Skill

This skill should be used when:
- Working with Neuropixels recordings (`.ap.bin`, `.lf.bin`, `.meta` files)
…

Read the whole file at its exact version.

How to install

The exact contents, by fingerprint
mdr add k-dense-ai/scientific-agent-skills/neuropixels-analysis@sha256:65985e85e9ac2206

The line at the top of this page pins the label v2.6, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.

Badge

mdr badge

[![mdr](https://markdownregistry.com/badge/art_hpb6uilzlyiggc6r.svg)](https://markdownregistry.com/a/art_hpb6uilzlyiggc6r)

3 badge image fetches in 30 days. What the badge shows.

Versions

The registry has recorded 7 versions of this file, between Jun 11, 2026 and Oct 1, 2026, about one every 19 days.

versioncommittedcommitsizeaudit
v2.6 latest2026-10-01 a92663a 20,153 BA view · diff
v2.52026-09-30 ce9e6e9 17,635 BA view · diff
v2.42026-09-02 1e5eeff 17,004 BA view · diff
v2.32026-07-31 4226ca8 16,046 BA view · diff
v2.22026-07-28 4fb7e0b 16,046 BA view · diff
v2.12026-07-26 b085e11 16,046 BA view · diff
git:20260611.c1150bd2026-06-11 c1150bd 16,196 BA view

Audit of the latest version

A  17 of 17 checks passed. Fixed automatic checks with no AI involved, so the same checks give the same answer every run.
  • pass: Frontmatter block present
  • pass: Frontmatter declares a name
  • pass: Frontmatter declares a description
  • pass: Size between 200 bytes and 200 KB (20153 bytes)
  • pass: No zero-width or bidi control characters
  • pass: No instruction hidden inside an HTML comment
  • pass: No link to an exfiltration or paste host
  • pass: No credential-shaped string
  • pass: No instruction to send local credentials anywhere
  • pass: No text hidden with inline styles
  • pass: No prompt-injection phrasing
  • pass: No curl or wget piped into a shell
  • pass: No recursive delete of root, home or parent
  • pass: No instruction to read or print local credentials
  • pass: No base64 blob over 200 characters
  • pass: No link to a raw IP address
  • pass: No script tag

Source

GitHub

k-dense-ai/scientific-agent-skills · 53,159 stars · license MIT · pushed 2026-10-19 · branch main

API

GET https://markdownregistry.com/api/v1/artifacts/art_hpb6uilzlyiggc6r
GET https://markdownregistry.com/api/v1/resolve?ref=k-dense-ai/scientific-agent-skills/neuropixels-analysis
GET https://markdownregistry.com/api/v1/blob/65985e85e9ac2206c92291446f543505b2b568bf1d622448e162ae6255e154dc

Your AI assistant does the legwork. You hear about the deals worth your word. Hand yours the standing instructions at modelranch.com and it joins the network that reads files like this one.

Guides: the SKILL.md format and its required fields · what to check before you install a skill · how to pin a skill to an exact version · where to find agent skills · keeping a team on the same skills · which agent file does what.

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Every file in k-dense-ai/scientific-agent-skills

Other files named neuropixels-analysis

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