polars-bio SKILL.md skillA
polars-bio from k-dense-ai/scientific-agent-skills is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.
mdr add k-dense-ai/scientific-agent-skills/polars-bio@v1.3Pins v1.3 in mdr.lock. Pin the fingerprint instead.
- Audit grade
- A, 17 of 17 checks passed
- Kind
- SKILL.md skill
- Repository
- k-dense-ai/scientific-agent-skills
- Path
skills/polars-bio/SKILL.md- Versions recorded
- 5
- Latest version
- v1.3, committed Oct 1, 2026
- First version recorded
- Jun 11, 2026
- Size
- 12,878 bytes
- Repository stars
- 56,497
- License
- MIT
Performs genomic interval overlap, nearest, merge, coverage, complement and subtraction on Polars DataFrames, and reads or writes BED, VCF, BCF, BAM, CRAM, GFF, GTF, FASTA and FASTQ data. Use for coordinate-aware genomic joins, read-depth analysis, lazy bioinformatics I/O, SQL queries or migration from bioframe.
Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.
What the file says
# polars-bio Use this skill for genomic interval arithmetic and bioinformatics file I/O through Polars and DataFusion. It targets **polars-bio 0.36.0**, tested with **Polars 1.44.2** on Python 3.13. The upstream package requires Polars >=1.37.1, PyArrow >=23.0.1,<25, DataFusion >=53,<54 and polars-config-meta >=0.3.2,<1. Keep this environment separate from packages needing incompatible Arrow or DataFusion releases. ```bash uv pip install "polars-bio==0.36.0" "polars==1.44.2" # Optional pandas interoperability (requires pandas >=3): uv pip install "polars-bio[pandas]==0.36.0" "polars==1.44.2" ``` Verify new releases against the [official release notes](https://github.com/biodatageeks/polars-bio/releases) and [package requirements](https://pypi.org/project/polars-bio/0.36.0/). The examples below with named files are **templates**: substitute actual files and check their schemas. The synthetic interval example and small local format round trips were executed during this review. ## Workflow 1. Record the assembly, contig naming, coordinate convention, strand policy and unit of analysis. Identical contig names do not prove identical assemblies. …
Read the whole file at its exact version.
How to install
mdr add k-dense-ai/scientific-agent-skills/polars-bio@sha256:b9dbf93b5d8dbaa3The line at the top of this page pins the label v1.3, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.
[](https://markdownregistry.com/a/art_wzhks7lwwoiwfmpo)
4 badge image fetches in 30 days. What the badge shows.
Versions
The registry has recorded 5 versions of this file, between Jun 11, 2026 and Oct 1, 2026, about one every 28 days.
| version | committed | commit | size | audit | |
|---|---|---|---|---|---|
| v1.3 latest | 2026-10-01 | a92663a | 12,878 B | A | view · diff |
| v1.2 | 2026-09-30 | ce9e6e9 | 16,590 B | A | view · diff |
| v1.1 | 2026-09-02 | 1e5eeff | 16,113 B | A | view · diff |
| v1.0 | 2026-07-26 | b085e11 | 15,155 B | A | view · diff |
| git:20260611.1b8fae3 | 2026-06-11 | 1b8fae3 | 15,160 B | A | view |
Audit of the latest version
- pass: Frontmatter block present
- pass: Frontmatter declares a name
- pass: Frontmatter declares a description
- pass: Size between 200 bytes and 200 KB (12878 bytes)
- pass: No zero-width or bidi control characters
- pass: No instruction hidden inside an HTML comment
- pass: No link to an exfiltration or paste host
- pass: No credential-shaped string
- pass: No instruction to send local credentials anywhere
- pass: No text hidden with inline styles
- pass: No prompt-injection phrasing
- pass: No curl or wget piped into a shell
- pass: No recursive delete of root, home or parent
- pass: No instruction to read or print local credentials
- pass: No base64 blob over 200 characters
- pass: No link to a raw IP address
- pass: No script tag
Source
k-dense-ai/scientific-agent-skills · 56,497 stars · license MIT · pushed 2026-11-02 · branch main
API
GET https://markdownregistry.com/api/v1/artifacts/art_wzhks7lwwoiwfmpo GET https://markdownregistry.com/api/v1/resolve?ref=k-dense-ai/scientific-agent-skills/polars-bio GET https://markdownregistry.com/api/v1/blob/b9dbf93b5d8dbaa3de4541449b828cd6199625c54956e8598f7552eefc30116f
Your AI assistant does the legwork. You hear about the deals worth your word. Hand yours the standing instructions at modelranch.com and it joins the network that reads files like this one.
Guides: the SKILL.md format and its required fields · what to check before you install a skill · how to pin a skill to an exact version · where to find agent skills · keeping a team on the same skills · which agent file does what.