bio-data-visualization-circos-plots SKILL.md skillA

bio-data-visualization-circos-plots from pku-yuangroup/openai4s is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.

Install it, pinned
mdr add pku-yuangroup/openai4s/bio-data-visualization-circos-plots@git:20260821.2d1b678

Pins git:20260821.2d1b678 in mdr.lock. Pin the fingerprint instead.

Audit grade
A, 17 of 17 checks passed
Kind
SKILL.md skill
Repository
pku-yuangroup/openai4s
Path
skills/bioskills/bio-data-visualization-circos-plots/SKILL.md
Versions recorded
1
Latest version
git:20260821.2d1b678, committed Aug 21, 2026
Size
13,746 bytes
Repository stars
662
License
MIT

Build circular genome visualizations using circlize (R), pyCirclize (Python), or Circos (Perl CLI) with ideogram tracks, multi-data tracks (scatter, histogram, heatmap), chord/link arcs for interactions, and explicit circos.clear() between plots. Covers when circular is appropriate vs when Cartesian wins (Cleveland-McGill 1984), karyograms, and chromosome adjacency in chord diagrams. Use when adjacency on the circle conveys meaning — chromosome-level overview, structural variants, Hi-C…

Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.

What the file says

## Version Compatibility

Reference examples tested with: circlize 0.4.16+ (R), pyCirclize 1.4+ (Python), Circos 0.69-9 (Perl CLI), ComplexHeatmap 2.18+ (uses circlize for color mapping).

Before using code patterns, verify installed versions match. If versions differ:
- R: `packageVersion('<pkg>')` then `?function_name`
- Python: `pip show <package>` then `help(module.function)`

If code throws ImportError, AttributeError, or TypeError, introspect the installed package and adapt the example to match the actual API rather than retrying.

# Circular Genome Plots (Circos)

**"Make a circos plot"** -> Render genome chromosomes around a circle with stacked tracks (histogram, scatter, heatmap) and arcs/chords showing interactions. Krzywinski 2009 *Genome Res* 19:1639 introduced the genre for genome-scale comparative views. The single decision that matters: **does the circular layout convey meaning that Cartesian cannot?**

- R: `circlize::circos.initializeWithIdeogram` + `circos.genomicTrack*` (Gu 2014)
- Python: `pyCirclize.Gcircle`
- CLI: Circos (Perl); config-driven; most flexible but steepest learning
…

Read the whole file at its exact version.

How to install

The exact contents, by fingerprint
mdr add pku-yuangroup/openai4s/bio-data-visualization-circos-plots@sha256:4ffdc05bc51025b5

The line at the top of this page pins the label git:20260821.2d1b678, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.

Badge

mdr badge

[![mdr](https://markdownregistry.com/badge/art_zzngfqimy5etqaid.svg)](https://markdownregistry.com/a/art_zzngfqimy5etqaid)

2 badge image fetches in 30 days. What the badge shows.

Versions

The registry has recorded 1 version of this file, committed on Aug 21, 2026.

versioncommittedcommitsizeaudit
git:20260821.2d1b678 latest2026-08-21 2d1b678 13,746 BA view

Audit of the latest version

A  17 of 17 checks passed. Fixed automatic checks with no AI involved, so the same checks give the same answer every run.
  • pass: Frontmatter block present
  • pass: Frontmatter declares a name
  • pass: Frontmatter declares a description
  • pass: Size between 200 bytes and 200 KB (13746 bytes)
  • pass: No zero-width or bidi control characters
  • pass: No instruction hidden inside an HTML comment
  • pass: No link to an exfiltration or paste host
  • pass: No credential-shaped string
  • pass: No instruction to send local credentials anywhere
  • pass: No text hidden with inline styles
  • pass: No prompt-injection phrasing
  • pass: No curl or wget piped into a shell
  • pass: No recursive delete of root, home or parent
  • pass: No instruction to read or print local credentials
  • pass: No base64 blob over 200 characters
  • pass: No link to a raw IP address
  • pass: No script tag

Source

GitHub

pku-yuangroup/openai4s · 662 stars · license MIT · pushed 2026-11-03 · branch main

API

GET https://markdownregistry.com/api/v1/artifacts/art_zzngfqimy5etqaid
GET https://markdownregistry.com/api/v1/resolve?ref=pku-yuangroup/openai4s/bio-data-visualization-circos-plots
GET https://markdownregistry.com/api/v1/blob/4ffdc05bc51025b509502e4f3b6351e74cd90d6d283d26e016a7dedfa8a396cd

Your AI assistant does the legwork. You hear about the deals worth your word. Hand yours the standing instructions at modelranch.com and it joins the network that reads files like this one.

Guides: the SKILL.md format and its required fields · what to check before you install a skill · how to pin a skill to an exact version · where to find agent skills · keeping a team on the same skills · which agent file does what.

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