bio-clinical-databases-dbsnp-queries SKILL.md skillA
bio-clinical-databases-dbsnp-queries from pku-yuangroup/openai4s is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.
mdr add pku-yuangroup/openai4s/bio-clinical-databases-dbsnp-queries@git:20260821.2d1b678Pins git:20260821.2d1b678 in mdr.lock. Pin the fingerprint instead.
- Audit grade
- A, 17 of 17 checks passed
- Kind
- SKILL.md skill
- Repository
- pku-yuangroup/openai4s
- Path
skills/bioskills/bio-clinical-databases-dbsnp-queries/SKILL.md- Versions recorded
- 1
- Latest version
- git:20260821.2d1b678, committed Aug 21, 2026
- Size
- 20,885 bytes
- Repository stars
- 662
- License
- MIT
Resolves rsIDs, navigates RsMergeArch/SNPHistory merge chains, and converts between rsID, SPDI, HGVS, and VCF representations using the dbSNP Build 156 JSON architecture. Use when normalizing variant identifiers, joining variant databases by cluster ID, or tracking deprecated rsIDs through historical merges.
Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.
What the file says
## Version Compatibility Reference examples tested with: myvariant 1.0+, requests 2.31+, biopython 1.83+, Entrez Direct 21.0+. dbSNP Build 156 (September 2022) is the current schema; Build 151 (2017) was the last with relational SQL dumps. Builds 152-155 dual-released JSON+SQL; 156+ is JSON-only. Before using code patterns, verify installed versions match. If versions differ: - Python: `pip show <package>` then `help(module.function)` to check signatures - CLI: `<tool> --version` then `<tool> --help` to confirm flags If code throws ImportError, AttributeError, or TypeError, introspect the installed package and adapt the example to match the actual API rather than retrying. The Variation Services REST API uses path-based versioning (`/variation/v0/`); E-utilities `db=snp` returns thin legacy summaries missing build-156 schema fields. # dbSNP Queries and rsID Normalization **'Look up this rsID / normalize variant representations'** -> Resolve rsIDs through merge chains, compute canonical SPDI, and convert between rsID, HGVS-g, HGVS-c, and VCF allele representations. - Python (aggregator): `myvariant.MyVariantInfo().getvariant(rsid, fields=['dbsnp', 'clinvar', 'gnomad_exome'])` …
Read the whole file at its exact version.
How to install
mdr add pku-yuangroup/openai4s/bio-clinical-databases-dbsnp-queries@sha256:ef96fdaca79a8eb7The line at the top of this page pins the label git:20260821.2d1b678, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.
[](https://markdownregistry.com/a/art_2drogpconsr566ll)
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Versions
The registry has recorded 1 version of this file, committed on Aug 21, 2026.
Audit of the latest version
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Source
pku-yuangroup/openai4s · 662 stars · license MIT · pushed 2026-11-03 · branch main
API
GET https://markdownregistry.com/api/v1/artifacts/art_2drogpconsr566ll GET https://markdownregistry.com/api/v1/resolve?ref=pku-yuangroup/openai4s/bio-clinical-databases-dbsnp-queries GET https://markdownregistry.com/api/v1/blob/ef96fdaca79a8eb79e6974b9cd203b7389d7959c1039df8cd883c22e0452a274
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