depmap SKILL.md skillA
depmap from k-dense-ai/scientific-agent-skills is an agent skill: a SKILL.md folder an AI agent loads when a task calls for it.
mdr add k-dense-ai/scientific-agent-skills/depmap@v1.2Pins v1.2 in mdr.lock. Pin the fingerprint instead.
- Audit grade
- A, 17 of 17 checks passed
- Kind
- SKILL.md skill
- Repository
- k-dense-ai/scientific-agent-skills
- Path
skills/depmap/SKILL.md- Versions recorded
- 4
- Latest version
- v1.2, committed Oct 1, 2026
- First version recorded
- Jun 11, 2026
- Size
- 13,887 bytes
- Repository stars
- 56,497
- License
- MIT
Retrieves and analyzes Cancer Dependency Map (DepMap) release data, including CRISPR Chronos gene effects, cancer model annotations, omics biomarkers, and PRISM drug sensitivity. Supports cancer-selective dependency, co-essentiality, and candidate synthetic-lethality analyses with release-aware identifiers and statistical checks.
Collected from public GitHub. Every version is saved exactly as it was and never changes. Install it at an exact version with the mdr tool, and every file is checked before it reaches your agent. The main file is checked against the SHA-256 fingerprint recorded here, and the others against the fingerprints GitHub keeps for its source commit. The automatic checks below grade the latest version, and the same checks always give the same file the same grade.
What the file says
# DepMap — Cancer Dependency Map ## When to use Use this skill to rank dependencies in cancer models, compare prespecified biomarker cohorts, inspect co-essentiality, or relate genetic dependencies to PRISM compound response. These analyses generate target and synthetic-lethality hypotheses; they do not establish clinical efficacy, a therapeutic window, or a causal interaction. DepMap integrates Broad and Sanger CRISPR screens and hosts independent RNAi and drug-screen datasets. Match each question to its assay and pinned release. RNAi DEMETER2 is a different perturbation modality, not an older CRISPR scoring method. ## 1. Discover a release, then obtain its files Use [DepMap Downloads](https://depmap.org/portal/data_page/) and the selected release's README and release notes. On review, the live catalogue's latest `DepMap Public` release was **26Q1**, dated 2026-04-01. Rediscover before new work; a release name or expected quarter is not evidence a release is available. ### Verified public endpoint `GET https://depmap.org/portal/api/no-captcha/download/files` returns a complete CSV catalogue, with no request body, API key, or pagination parameters. Required …
Read the whole file at its exact version.
How to install
mdr add k-dense-ai/scientific-agent-skills/depmap@sha256:893eb02a2dc8a77eThe line at the top of this page pins the label v1.2, which is what most people want. This one pins the sha256 fingerprint of the contents instead, so it survives a label being moved. Either way the exact version is written to mdr.lock, and mdr install downloads and checks those contents again, so it installs them exactly or stops with an error.
[](https://markdownregistry.com/a/art_ceeco4jj3brsajcq)
3 badge image fetches in 30 days. What the badge shows.
Versions
The registry has recorded 4 versions of this file, between Jun 11, 2026 and Oct 1, 2026, about one every 37 days.
| version | committed | commit | size | audit | |
|---|---|---|---|---|---|
| v1.2 latest | 2026-10-01 | a92663a | 13,887 B | A | view · diff |
| v1.1 | 2026-09-30 | ce9e6e9 | 11,822 B | A | view · diff |
| v1.0 | 2026-07-26 | b085e11 | 11,292 B | A | view · diff |
| git:20260611.1b8fae3 | 2026-06-11 | 1b8fae3 | 11,297 B | A | view |
Audit of the latest version
- pass: Frontmatter block present
- pass: Frontmatter declares a name
- pass: Frontmatter declares a description
- pass: Size between 200 bytes and 200 KB (13887 bytes)
- pass: No zero-width or bidi control characters
- pass: No instruction hidden inside an HTML comment
- pass: No link to an exfiltration or paste host
- pass: No credential-shaped string
- pass: No instruction to send local credentials anywhere
- pass: No text hidden with inline styles
- pass: No prompt-injection phrasing
- pass: No curl or wget piped into a shell
- pass: No recursive delete of root, home or parent
- pass: No instruction to read or print local credentials
- pass: No base64 blob over 200 characters
- pass: No link to a raw IP address
- pass: No script tag
Source
k-dense-ai/scientific-agent-skills · 56,497 stars · license MIT · pushed 2026-11-02 · branch main
API
GET https://markdownregistry.com/api/v1/artifacts/art_ceeco4jj3brsajcq GET https://markdownregistry.com/api/v1/resolve?ref=k-dense-ai/scientific-agent-skills/depmap GET https://markdownregistry.com/api/v1/blob/893eb02a2dc8a77e61260dfb74b2acdf6c85e08f33028329d73657a23d398586
Your AI assistant does the legwork. You hear about the deals worth your word. Hand yours the standing instructions at modelranch.com and it joins the network that reads files like this one.
Guides: the SKILL.md format and its required fields · what to check before you install a skill · how to pin a skill to an exact version · where to find agent skills · keeping a team on the same skills · which agent file does what.
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